某三级综合医院住院患者多药耐药菌感染分析  

Multidrug-resistant bacteria infections in hospitalized patients of a three-A general hospital

作　　者：王勇[1] 潘磊[1] 薛文英[2] 宋志香[2] 

机构地区：[1]首都医科大学附属北京世纪坛医院老年医学科,北京100038 [2]首都医科大学附属北京世纪坛医院感染管理处,北京100038

出　　处：《中华医院感染学杂志》2013年第10期2492-2494,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析2011年度某三级综合医院住院患者多药耐药菌感染的情况,为减少多药耐药感染提供有效数据。方法采用回顾性方法分析某三级综合医院住院患者2011年1-12月送检标本中多药耐药菌所占比例、标本来源及感染科室分布。结果共检出6种多药耐药菌2543株,占全院总分离菌的8.93%,73.41%的多药耐药菌来源于痰液,其次是尿液;铜绿假单胞菌及鲍氏不动杆菌成为主要的多药耐药菌,分别占多药耐药菌的31.81%及30.00%;多药耐药菌感染科室分布以ICU为主,占48.72%,其次呼吸内科,占34.13%。结论多药耐药菌导致医院内难治性感染的比例不断上升,使抗菌药物面临选择的压力与挑战,加强多药耐药菌的监测、减少多药耐药菌的发生及流行具有重要意义。OBJECTIVE To investigate and analyze of multidrug-resistant organism（MDRO） infections in hospitalized patients in a three-A general hospital in 2011 so as to provide reliable data for reducing the MDROs infections. METHODS The specimen source, clinical distribution, and constituent ratios of the MDROs isolated from clinical specimens between Jan and Dec 2011 were retrospectively analyzed. RESULTS A total of 2543 strains of MDROs in 6 species were isolated, accounting for 8.93% among all the isolated bacteria; 73.41% of the MDROs were isolated from the sputum specimens, followed by the urine. The multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii were dominant in the MDROs, accounting for 31. 81% and 30. 00%, respectively. 48.72% of the MDROs infections distributed in ICU, 34. 13% in the respiratory medicine department. CONCLUSION The refractory infections caused by the MDROs are increased, which brings the use of antibiotics the great pressure and challenge. It is of great significance in reducing the outbreak and prevalence of the MDROs to strengthen the monitoring of MDROs.

关 键 词：综合医院 多药耐药菌 监测 

分 类 号：R181.32[医药卫生—流行病学]