血塞通软胶囊对老年脑血管病颈动脉粥样硬化软斑块的影响  

Effect of Xuesaitong Soft Capsule on Soft Plaque in Elderly Patients with Cerebrovascular Carotid Atherosclerosis Disease

作　　者：丁俊蓉[1] 周益伟 楚艳艳[1] 肖新政[1] 

机构地区：[1]潍坊市妇幼保健院,潍坊261011 [2]潍坊护理职业学院,潍坊261041

出　　处：《国际老年医学杂志》2013年第3期101-104,共4页International Journal of Geriatrics

摘　　要：目的：观察血塞通软胶囊对老年颈动脉粥样硬化斑块中软斑块的临床疗效。方法：将240例患者按随机数字表法分成两组各120例。对照组采用肠溶阿司匹林、辛伐他汀常规治疗；治疗组在对照组治疗基础上加用血塞通软胶囊，两组均治疗6个月为1个疗程，随访1年。结果：两组治疗后软斑性质、数目、体积均较治疗前显著改善，且治疗组在软斑消退、软斑转为硬斑、软斑数目、软斑体积等方面优于对照组（t=3．525，P〈0．01）。治疗组心脑血管事件发生和再住院情况优于对照组（t=3．678，P〈0．01）。结论：血塞通软胶囊可有效治疗老年颈动脉粥样硬化软斑块，降低心脑血管疾病事件的发生率。OBJECTIVE ： To observe the clinical effect of Xuesaitong Soft Capsule （XSC） on soft plaque in elderly patients with cerebrovascular carotid atherosclerosis disease. METHODS： 240 patients with cerebrovascular carotid atherosclerosis disease were randomly divided into two groups： 120 patients in the control group （n = 120） received conventional therapy （aspirin and simvastatin） and treatment group （n = 120） were treated by conventional therapy plus XSC exclusively. Both groups received the treatment for 6 months and tracked follow - up 1 year. RESULTS： In each group before and after treatment, the nature, number and size of soft plaque were apparently improved after treatment. And soft plaques faded, soft plaque to a hard plaque, the number of soft plaque and soft plaque volume in the treatment group were all better then those in the control group （ t = 3. 525, P 〈 0. 01 ）, Cardiovascular and cerebrovascular events and re - hospitalization in the treatment group were superior to the control group （ t = 3. 678, P 〈 0. 01 ）. CONCLUSION： XSC is effective in the treatment of carotid atherosclerosis soft plaque and it can significantly decrease the incidence rate of cardiovascular and cerebrovascular disease.

关 键 词：颈动脉粥样硬化斑块 软斑 血塞通软胶囊 脑血管病 

分 类 号：R543.4[医药卫生—心血管疾病]