264例无精子症患者染色体分析  

Chromosomal karyotypes analysis of 264 cases with azoospermia

作　　者：刘宇[1] 赵应斌[1] 黄紫红[1] 

机构地区：[1]柳州市人民医院遗传室,广西柳州545006

出　　处：《中国优生与遗传杂志》2013年第5期62-63,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨无精子症和染色体异常之间的关系。方法通过264例无精子症患者的外周血淋巴细胞培养,应用G,C显带技术进行染色体核型分析。结果查出异常的染色体核型83例,异常核型检出率为31.44%。结论染色体异常是导致无精子症的重要原因之一,对无精子症患者进行染色体检查对临床诊断具有重要意义,可避免必不要的盲目诊治。Objective： To investigate the relationship between abnormal karyotype and azoospermia. Methods： Lymphocytes were cultured from peripheral blood of 264 azoospermia patients. Chromosomal karyotypes was analyzed by using G banding and C banding. Results： Among 264 cases there were 83 cases with abnormal karyotypes （31.44% ）. Conclusion： Abnormal chromosome is an impor- tant factor that could result in azoospermia patients. The examination of chromosomal karyotypes is necessary not only useful diagnosis but also avoid blindness therapy in such patients.

关 键 词：无精子症 染色体 异常核型 

分 类 号：R698.2[医药卫生—泌尿科学]