先天性甲状腺功能减低症伴病理性黄疸61例分析  

The analysis of sixty-one children with congenital hypothyroidism and pathologic jaundice

作　　者：郑敏 潘莉珍 谢莉 蔡稔 

机构地区：[1]广西柳州市妇幼保健院内分泌遗传代谢病科,广西柳州545001

出　　处：《中国优生与遗传杂志》2013年第5期134-135,共2页Chinese Journal of Birth Health & Heredity

基　　金：广西壮族自治区卫生厅课题 基金号:Z2012518

摘　　要：目的观察先天性甲状腺功能减低症(CH)患儿病理性黄疸的发生情况,研究黄疸与甲减程度的关系。方法回顾性分析2007年1月～2011年12月在我院确诊的127例CH患儿的资料。结果 127名CH患儿中伴有病理性黄疸的61例,其中2例CH男婴合并G6PD缺乏,1例男婴合并血红蛋白HbH病。合并病理性黄疸的CH患儿血清TSH水平与无病理性黄疸的CH患儿比较显著升高,血清FT4与FT3水平显著低下。结论 CH患儿伴病理性黄疸组的甲状腺功能较不伴黄疸的更为低下。对CH患儿,必须动态监测黄疸状况并注意其他引起黄疸的合并症。Objective： To observe the effluence of pathologic jaundice in children with congenital hypothyroidism（CH） and to study the relationship between the degree of thyroid hormones and pathologic jaundice.Methods： To retrospective analyze case history of the 127 cases children with congenital hypothyroidism being diagnosised in our hospital.Results： 61 cases were accompanied pathologic jaundice in the 127 cases CH children.Among the total two boys were accompanied G6PD deficiency and one boy was accompanied HbH disease.The lever of TSH in children accompanied pathologic jaundice was significant higher than that in children who were not accompanied pathologic jaundice.The lever of FT4 and FT3 in the first was significant lower than that in the latter.Conclusions： The thyroid function in children accompanied pathologic jaundice was lower than that in children who were not accompanied pathologic jaundice.The jaundice must be monitored and complication must be observed.

关 键 词：先天性甲状腺功能减退症 黄疸 甲状腺功能 

分 类 号：R725.8[医药卫生—儿科]