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作 者:Lina Sui Guang-Hui Liu Juan Carlos Izpisua Belmonte
机构地区:[1]National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Aeademy of Sci- ences, Beijing 100101, China [2]Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA [3]Center for Regen- erative Medicine in Barcelona, Dr Aiguader 88, 08003 Barcelona, Spain
出 处:《Cell Research》2013年第5期592-594,共3页细胞研究(英文版)
摘 要:Successful derivation of pancreatic progenitors from human embryonic stem ceils (hESCs) in vitro and further differentiation towards functional p cells in vivo may create the possibility of using hESC-derived pancreatic progenitors (PPs), instead of derived ceils, as an alternative transplantable source in cell replacement therapy. Here we discuss present approaches, as well as future alternatives, in the fields of basic and clinic research on p cell differentiation, derivation and transplantation.
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