原发性高血压患者动脉僵硬度与心脏重构的相关性研究  

Correlation between arterial stiffness and left ventricular function in patients with primary hypertension

作　　者：曾锋 汤达鹏 余钷 罗柳玲 刘建芬 梁国华 

机构地区：[1]宝钢集团广东韶关钢铁有限公司医院,韶关512123

出　　处：《中国循证心血管医学杂志》2013年第2期170-171,共2页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的探讨原发性高血压患者动脉僵硬度与左心功能的相关性。方法纳入原发性高血压患者79例,根据颈桡脉搏波传导速度(PWV)将患者分为对照组(PWV<0.9m/s,n=42)和观察组(PWV≥0.9m/s,n=37),两组患者均行心脏彩超检查比较心功能参数差异。结果两组患者间左室舒张末期内径(LVEDd)、左室射血分数(LVEF)、左室质量指数(LVMI)、二尖瓣舒张早期血流峰速(E)、舒张晚期血流峰速(A)及二者比值(E/A)差异具有统计学意义(P<0.05);Pearson相关分析显示PWV与LVMI存在显著的相关性(r=0.347,P<0.05)。结论原发性高血压患者动脉僵硬度与左心重构存在显著的相关性,在临床上检测动脉弹性对于评价高血压患者心脏重构具有显著的临床意义。Objective To discuss the correlation between arterial stiffness and left ventricular function in patients with primary hypertension. Methods The patients （ n=79 ） were divided, according to carotid-radial pulse wave velocity （ PWV ） , into control group （ PWV〈0.9 m/s, n=42 ） and observation group （ PWV≥0.9 m/s, n=37 ） . All patients were given the examination of color Doppler echocardiography, and the difference in cardiac function parameters were compared between two groups. Results The difference in cardiac function parameters, including left ventricular end-diastolic inner diameter （ LVEDd ） , left ventricular ejection fraction （ LVEF ） , left ventricular mass index （ LVMI ） , mitral early diastole inflow velocity （ E ） , late diastole inflow velocity （ A ） and ratio of E to A （ E/A ） , had statistical significance between two groups （ P〈0.05 ） . Pearson correlation analysis showed that there was a significant correlation between PWV and LVMI （ r=0.347, P〈0.05 ） . Conclusion The arterial stiffness is significantly correlated to left ventricular function, and examination of arterial elasticity is significant for reviewing ventricular remodeling in in patients with primary hypertension in clinic.

关 键 词：原发性高血压 动脉僵硬度 左心功能 脉搏波传导速度 

分 类 号：R544.1[医药卫生—心血管疾病]