Prostate cancer research in China  

作　　者：Shan-Cheng Ren Rui Chen Ying-Hao Sun 

机构地区：[1]Department of Urology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai 200433, China

出　　处：《Asian Journal of Andrology》2013年第3期350-353,共4页亚洲男性学杂志（英文版）

基　　金：This work was supported by grants from the National Basic Research Program of China （No. 2012CD518300）, the National Natural Science Foundation of China （No. 81101946）, and the Prostate Cancer Foundation Young Investigator Award, and Shanghai Pujiang Program （12PJD008）.

摘　　要：Prostate cancer （PCa） research in China has been on a rocketing trend in recent years. The first genome-wide association study （GWAS） in China identified two new PCa risk associated single nucleotide polymorphisms （SNPs）. Next generation sequencing is beginning to be used, yielding novel findings： gene fusions, long non-coding RNAs and other variations. Mechanisms of PCa progression have been illustrated while various diagnosis biomarkers have been investigated extensively. Personalized therapy based on genetic factors, nano-medicine and traditional Chinese medicine has been the focus of experimental therapeutic research for PCa. This review intends to shed light upon the recent progress in PCa research in China and points out the possible breakthroughs in the future.Prostate cancer （PCa） research in China has been on a rocketing trend in recent years. The first genome-wide association study （GWAS） in China identified two new PCa risk associated single nucleotide polymorphisms （SNPs）. Next generation sequencing is beginning to be used, yielding novel findings： gene fusions, long non-coding RNAs and other variations. Mechanisms of PCa progression have been illustrated while various diagnosis biomarkers have been investigated extensively. Personalized therapy based on genetic factors, nano-medicine and traditional Chinese medicine has been the focus of experimental therapeutic research for PCa. This review intends to shed light upon the recent progress in PCa research in China and points out the possible breakthroughs in the future.

关 键 词：prostate cancer （PCa） genome-wide association study （GWAS） single nucleotide polymorphisms （SNPs） China 

分 类 号：Q78[生物学—分子生物学] TS255[轻工技术与工程—农产品加工及贮藏工程]