The SBA-15/SO_3H nanoreactor as a highly efficient and reusable catalyst for diketene-based,four-component synthesis of polyhydroquinolines and dihydropyridines under neat conditions  

作　　者：Sadegh Rostamnia Fatemeh Pourhassan 

机构地区：[1]Organic and Nano Group(ONG),Department of Chemistry,Faculty of Science,University of Maragheh

出　　处：《Chinese Chemical Letters》2013年第5期401-403,共3页中国化学快报（英文版）

摘　　要：An efficient diketene ring-opening synthesis of polyhydroquinoline derivatives using SBA-15 sulfonic acid modified mesoporous substrates a green and reusable catalyst in a single-pot four-component coupling reaction of diketene,alcohol,enamine,and aldehydes is reported.Dihydropyridine derivatives based on neat adduct of diketene,alcohols and aldehydes using SBA-15/SO_3H nanoreactor as catalyst via a four-component reactions are also synthesized.The advantages of the present method include the use of a small amount catalyst,simple procedure with an easy filterable work-up,waste-free,green and direct synthetic method with an excellent yield of products with efficient use of catalyst and a short reaction time.An efficient diketene ring-opening synthesis of polyhydroquinoline derivatives using SBA-15 sulfonic acid modified mesoporous substrates a green and reusable catalyst in a single-pot four-component coupling reaction of diketene,alcohol,enamine,and aldehydes is reported.Dihydropyridine derivatives based on neat adduct of diketene,alcohols and aldehydes using SBA-15/SO_3H nanoreactor as catalyst via a four-component reactions are also synthesized.The advantages of the present method include the use of a small amount catalyst,simple procedure with an easy filterable work-up,waste-free,green and direct synthetic method with an excellent yield of products with efficient use of catalyst and a short reaction time.

关 键 词：SBA-15/SO3H NANOREACTOR Diketene POLYHYDROQUINOLINE 

分 类 号：O643.36[理学—物理化学]