异丙酚对学习记忆功能影响的实验研究  

Experimental research of propofol on learning and memory function

作　　者：徐晓东[1] 张良成[1] 

机构地区：[1]福建医科大学附属协和医院麻醉科,福州350001

出　　处：《中国实用医药》2013年第12期7-9,共3页China Practical Medicine

摘　　要：随着对全麻原理的深入认识,全身麻醉药物对学习记忆功能的影响日益受到重视。异丙酚作为目前最常用的静脉全麻药,除了具有镇静、催眠的作用外,还具有遗忘作用,这可能是导致术后认知功能障碍的重要原因之一。本文综述近年来异丙酚对学习记忆功能影响的研究成果及可能的相关机制,以期获得详细全面的认识。With in-depth understanding of the mechanism of general anesthesia, the effects of general anesthetics on learning and memory are taken seriously increasingly. As the most widely used intravenous anesthetic, propofol has sedative and hypnotic function, and its forgotten role may be the one of the important causes of postoperative cognitive dysfunction （POCD）. This paper reviews the recent research of propofol on learning and memory function and related possible mechanism, in order to obtain detailed knowledge.

关 键 词：异丙酚 麻醉药 学习 记忆 

分 类 号：R614[医药卫生—麻醉学]