糖尿病动物模型研究进展  

Advance Research on Animal Models of Diabetes Mellitus

作　　者：孙国鹏[1] 尹国安[2] 张艳芳[1] 

机构地区：[1]新乡学院,河南新乡453003 [2]黑龙江八一农垦大学动物科技学院

出　　处：《中外医学研究》2013年第14期149-151,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：新乡学院博士科研启动基金(项目编号:1399020097);新乡学院科研创新基金(项目标号:2011XXXYCX004)

摘　　要：糖尿病动物模型在糖尿病以及其并发症发病机制的研究中应用极其广泛,并且已有较长历史。除此之外,所有针对糖尿病治疗的措施,包括胰腺细胞的移植,甚至是预防策略,都要预先在动物模型上开展并观察。因此,对糖尿病动物模型进行研究和优化,使其更接近人类糖尿病发病过程,将有助于深入研究糖尿病及其并发症的发病机制,并为治疗和预防糖尿病奠定重要基础。Animal models have been used extensively in diabetes research for a long time. Apart from their use in studying the pathogenesis of the disease and its complications, all new treatments for diabetes, including islet cell transplantation and preventative strategies, are initially investigated in animals. Therefore, improving experimental diabetic animal models and looking for excellent models of human-like pathogenic process of diabetes become much more significant in the pathogenesis of diabetes and its complications.

关 键 词：糖尿病 实验性动物模型 自发性 诱导性 

分 类 号：R587.1[医药卫生—内分泌]