曼月乐环对子宫腺肌病临床疗效的随访观察  

The follow-up visit and observation of adenomyosis treated with Mirena

作　　者：申爱荣[1] 冯怡凡[1] 郜祥[1] 李洁[1] 王芳[1] 

机构地区：[1]郑州大学第三附属医院妇产科,450052

出　　处：《中国实用医刊》2013年第11期23-24,共2页Chinese Journal of Practical Medicine

摘　　要：目的探讨左炔诺孕酮宫内缓释系统（LNG-IUS，商业名曼月乐）治疗子宫腺肌病的临床疗效及不良反应。方法随访2010年8月至2012年4月期间在郑州大学第三附属医院门诊就诊的宫内放置曼月乐环的53例患有子宫腺肌病患者，观察曼月乐环旗置前及放置后的1、3、6个月的痛经评分、PBAC月经量评分、子宫体积及内膜厚度等多项改变及使用曼月ft．环后相关的不良反应。结果曼月乐治疗前后患者痛经症状显著减轻（P〈0．01），月经量显著减少（P〈n01），子宫内膜变薄（P〈0．01）；子宫体积稍有缩小，但差异无统计学意义（P〉n05）。伴随阴道不规则点滴出血、围绝经期症状、阴道干燥、骨质疏松等不良反应。结论左炔诺孕酮宫内缓释系统是治疗子宫腺肌病的一种有效治疗方法。Objective To investigate the clinical effect and sides effects of levonorgestrel-relea- sing intrauterine （Mirena） in the treatment of adenomyosis. Methods Fifty-three cases of adenomyosis treated with levonorgestrel-releasing intrauterine system in the third affiliated hospital of Zhengzhou uni- versity during August 2010 and April 2012 were followed-up. The change of dysmenorrhea and menstrual volume, sides effects before and after 1,3, 6 months insertion respectively were observed. Results The grades of both postoperative dysmenorrhea, menstrual volume and endometrial thickness markedly de- creased, with statistical significance （P 〈 0.01 ）. The uterine volume slightly reduced, but there was no statistical significant differece before and after treatment （P 〉 0.05 ）. The main side effects were little va- ginal bleeding, menopausal symptom, colpoxerosis, osteoporosis and so on. Conclusions Mirena was an effective method in the treatment of adenomyosis.

关 键 词：左炔诺孕酮宫内缓释系统 子宫腺肌症 随访 

分 类 号：R711.7[医药卫生—妇产科学]