分子蒸馏法浓缩α-生育酚的工艺研究  

Research on Molecular Distillation for Concentrating α-Tocopherol

作　　者：丁朝中[1] 林文[1] 陈乐清[1] 王志祥[1] 

机构地区：[1]中国药科大学制药工程教研室,南京210009

出　　处：《中国粮油学报》2013年第5期44-48,共5页Journal of the Chinese Cereals and Oils Association

摘　　要：采用三级分子蒸馏,从大豆油脱臭馏出物中浓缩α-生育酚。一、二级分子蒸馏通过单因素试验确定优选工艺;三级分子蒸馏采用响应曲面法对操作条件进行优化。试验结果表明,将大豆油脱臭馏出物进行甲酯化预处理后,再通过3次分子蒸馏,并结合两次脱除甾醇,可明显提高生育酚质量分数,α-生育酚质量分数从0.48%提高至3.59%。In this paper,α -tocopherol was concentrated from molecular distillation. Single -factor experiments were carried out to soybean oil deodorizer distillate by three -stage determine the preferred process of the first and second stage molecular distillation ; The operating conditions of the third - stage molecular distillation were optimized by response surface methodology. The experimental results show that：Soybean oil deodorizer distillate was operated by methyl esterification pretreatment, followed by three - stage molecular distillation and then combined with twice removal of sterol, the purity of the product can be significantly improved. The mass fraction of α - tocopherol increased from 0.48% to 3.59%.

关 键 词：大豆油脱臭馏出物 分子蒸馏 Α-生育酚 响应曲面分析 

分 类 号：TQ466.5[化学工程—制药化工]