螺吡喃分子光开关  

Spiropyran-Based Molecular Photoswitches

作　　者：张国峰[1] 陈涛[1] 李冲[1] 龚文亮[1] Matthew P.Aldred 朱明强[1] 

机构地区：[1]华中科技大学武汉光电国家实验室(筹),武汉430074

出　　处：《有机化学》2013年第5期927-942,共16页Chinese Journal of Organic Chemistry

基　　金：国家基础研究计划(No.2013CB922104);国家自然科学基金(Nos.20874025,21174045);国家自然科学基金委外国青年学者研究基金(No.21150110141);中国博士后科学基金(No.20100480065);中国博士后特别资助基金(No.2012T50642)资助项目~~

摘　　要：螺吡喃是一类研究最早,最广泛的有机光致变色分子.利用光照前后螺吡喃分子结构上和光化学与光物理性质的变化,将其作为分子光开关材料被广泛应用于光电器件、化学传感、药物控制释放等领域.综述了部分螺吡喃分子光开关的合成和性质及其在相关领域中的应用,对其作为新型的荧光探针未来在生物成像领域的应用做了展望.Spiropyran is one of the classic photochromic compounds, which undergoes photoisomerization under ultraviolet exposure with its structure transformed from a non-polar, closed and colorless spiro-form to a highly polar, open and colorful cyanine-form with extended n-electron delocalization. This has encourged researchers to employ this material with unique photochemical and photophysical properties as a molecular photoswitch in the field of optoelectronic devices, chemical biosensing, controlled release drug delivery and so on. In this review, noticeable designs, synthesis, properties of some spiropyran derivatives and their applications in relative fields are summarized. Finally, as a promising fluorescent probe, the future developing prospects in bioimaging are discussed and highlighted.

关 键 词：螺吡喃 分子光开关 生物成像 

分 类 号：O623[理学—有机化学]