米索前列醇配伍盐酸丁卡因凝胶在绝经妇女门诊宫腔镜检查术中的应用  

The clinical value of misoprostol combined with tetracaine rubber paste for hysteroscopy in postmenopausal women at outpatient

作　　者：杨志海[1] 邹辉[1] 

机构地区：[1]大连医科大学附属第一医院妇产科,大连116011

出　　处：《现代预防医学》2013年第11期2047-2048,共2页Modern Preventive Medicine

摘　　要：目的观察米索前列醇配伍盐酸丁卡因凝胶在绝经后妇女门诊宫腔镜检查术时软化宫颈及减少术中疼痛效果。方法宫腔镜检查术104例随机分为两组,实验组52例在术前3h阴道穹隆置入米索前列醇0.3mg,术前5min盐酸丁卡因凝胶5ml注入宫颈管,对照组52例仅在术前以医用液体石蜡5ml润滑宫颈管。观察两组间的宫颈软化情况及术中疼痛情况。结果实验组,宫颈充分软化16例(30.8%),部分软化29例(55.8%),疼痛3例(5.5%);对照组宫颈充分软化0例,部分软化17例(32.7%),疼痛21例(40.4%),两组比较差异有统计学意义(P﹤0.05)。结论绝经后妇女门诊宫腔镜检查术前阴道置米索前列醇并配伍盐酸丁卡因凝胶能够提高手术成功率,减轻疼痛,应该广泛推广。OBJECTIVE To evaluate the clinical value of misoprostol combined with tetracaine rubber paste for hysteroscopy in postmenopausal women at outpatient. METHODS A total of 104 women were recruited and allocated to 2 groups：experimental group：women were given misoprostol 0.3mg vaginally 3 hours before operation and were given tetracaine rubber paste in cervical canal 5 minutes before operation;control group：women were given liquid paraffin in cervical canal 5 minutes before operation. The effects of preoperative cervical preparations and the pain during operation in 2 groups were compared. RESULTS In experimental group,16 cases were fully softening（30.8%）,29 cases were part of the softening（55.8%）,3 cases felt pain（5.5%）;in control group,0 case was fully softening,17 cases were part of the softening（32.7%）,21 cases felt pain（40.4%）. The differences in 2 groups were significant（P﹤0.05）. CONCLUSION Misoprostol combined with tetracaine rubber paste for hysteroscopy in postmenopausal women at outpatient can improve the success rate of operation,and alleviate the pain.It should be used for the preoperative preparations for postmenopausal women.

关 键 词：米索前列醇 盐酸丁卡因凝胶 绝经妇女 宫腔镜 

分 类 号：R981[医药卫生—药品]