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作 者:江真明
机构地区:[1]四川省成都市青白江区人民医院内科,四川成都610300
出 处:《现代预防医学》2013年第11期2170-2172,共3页Modern Preventive Medicine
摘 要:目的研究早期血糖水平是否可以作为老年社区获得性肺炎患者预后的预测因素。方法采用前瞻性队列研究方法,将2010年1月~2011年12月四川省成都市青白江区人民医院内科收住入院符合纳入标准的247例老年社区获得性肺炎患者纳入研究。根据患者入院时静脉血糖水平分别分为≤3.9mmol/L组、4.0~7.7mmol/L组、7.8~11.0mmol/L组及≥11.1mmol/L组,分别观察患者抗感染治疗时间、住院时间、入院后1个月及6个月病死率。结果社区获得性肺炎患者入院时血糖≤3.9mmol/L和≥11.1mmol/L两组抗感染治疗时间、住院时间、入院后1个月及6个月病死率均较4.0~7.7mmol/L组和7.8~11.0mmol/L组患者显著增高(P﹤0.05)。7.8~11.0mmol/L组抗感染治疗时间较4.0~7.7mmol/L组显著增加(P﹤0.05)。4.0~7.7mmol/L组和7.8~11.0mmol/L组两组患者住院时间、入院后1个月及6个月病死率差异无统计学意义(P﹥0.05)。结论早期血糖异常(血糖≤3.9mmol/L或≥11.1mmol/L)是老年社区获得性肺炎患者预后不佳的重要独立预测因素,针对急性期血糖异常患者应加强治疗及护理,以改善预后。OBJECTIVE To study whether early blood glucose is the predictive factor of elderly community acquired pneumonia patients or not. METHODS According to inclusion criteria,247 elderly community acquired pneumonia inpatients in Qingbaijiang People’s Hospital in Chengdu,Sichuan Province from Jan 2010 to Dec 2011,were studied with prospective cohort study;According to the levels of venous blood glucose in admission,all patients were divided into four groups:≤3.9 mmol/L,4.0-7.7 mmol/L,7.8-11.0 mmol/L and ≥11.1mmol/L,then observed anti-infective therapy time,length of stay and fatality rates of 1 month and 6 months after admission. RESULTS Anti-infective therapy time,length of stay and fatality rate of 1 month and 6 months after admission of community acquired pneumonia patients with ≤3.9mmol/L and ≥11.1mmol/L were higher in than those of 4.0-7.7 mmol/L group and 7.8-11.0 mmol/L group(P﹤0.05),and anti-infective therapy time of 7.8-11.0 mmol/L group was higher than that of 4.0-7.7 mmol/L group(P﹤0.05). There were no differences in length of stay and fatality rate of 1 month and 6 months after admission between 4.0-7.7 mmol/L group and 7.8-11.0 mmol/L group(P﹥0.05). CONCLUSION Early pathoglycemia(blood glucose ≤3.9 mmol/L or ≥11.1mmol/L)is the important independent predictive factor of bad prognosis of elderly patients,so therapy and nursing care for acute pathoglycemia patients should be strengthened to improve prognosis.
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