氟斑牙检出率与病区土壤化学元素含量相关性研究  

Correlation between prevalence of dental fluorosis and soil chemical elements in endemic fluorosis areas

作　　者：闫菊[1] 钟朝晖[1] 黄巧[1] 王力 雍开文 张茂忠 罗兴建[4] 晏维[4] 

机构地区：[1]重庆医科大学公共卫生学院流行病学教研室,400016 [2]重庆市地质矿产勘查开发局 [3]重庆市地勘局川东南地质大队 [4]重庆市疾病预防控制中心

出　　处：《中华地方病学杂志》2013年第3期303-308,共6页Chinese Journal of Endemiology

基　　金：重庆市地质矿产勘探开发局资助（渝地勘科字[2010]第2号）

摘　　要：目的探索土壤中的化学元素与氟斑牙的关系，为地方性氟中毒的防治提供科学依据。方法2011年，在巫山县与奉节县的55个乡（镇）中，采取整群随机抽样方法，选择38个乡（镇），采用Dean法对所有8—12岁儿童进行氟斑牙检查，并检测表层土壤中氟（F）、锌（Zn）、铜（Cu）、碘（I）、硒（Se）、镉（Cd）、铬（Cr）、砷（As）、镍（Ni）、汞（Hg）、铅（Pb）11种元素的含量。采用Spearman相关分析方法，分析氟斑牙检出率与土壤化学元素含量的相关性。结果巫山县儿童氟斑牙检出率与表层土壤氟、镉含量呈正相关，与表层土壤铜、锌、硒含量呈负相关，相关系数分别为1．0000、0．9053、-0．6617、-0．7353、-0．5143（P均〈0．05）。奉节县儿童氟斑牙检出率与表层土壤氟、镉含量呈正相关，与表层土壤铜、锌、硒含量呈负相关，相关系数分别为0．9959、0．9298、-0．5728、-0．8308、-0．6533（P均〈0．05）。结论巫山县和奉节县儿童氟斑牙检出率与表层土壤氟、镉、铜、锌、硒含量相关，应对这些元素与地方性氟中毒的关系进行深入研究。Objective To explore the correlation between chemical elements in soil and dental fluorosis and to provide a scientific basis for prevention of endemic fluorosia Methods In 2011, using cluster sampling, totally 38 of 55 townships （towns） in Fengjie and Wushan Counties were selected as investigation spots. Dental fluorosis of children aged 8 to 12 were examined with Dean index in all individuals from the sampled townships （towns）. We also detected the content of fluorine（F）, zinc（Zn）, copper（Cu）, iodine（I）, selenium（Se）, cadmium （Cd）, chromium （Cr）, arsenic （As）, nickel（Ni）, mercury （Hg） and lead （Pb） in topsoil of sampled townships （towns）. Using Spearman rank correlation analysis the correlation between dental fluorosis prevalence and the content of chemical elements in the topsoil of selected townships（towns） was analyzed. Results Children＇s dental fluorosis prevalence was positively correlated with surface soil F and Cd content in Wushan County, but negatively correlated with the content of Cu, Zn and Se, and the correlation coefficients were 1.0000, 0.9053, - 0.6617, - 0.7353 and - 0.5143, respectively （P 〈 0.05）. Children＇s dental fluorosis detection rate was also positively correlated with the surface soil content of F and Cd in Fengjie County, but also negatively correlated with the content of Cu, Zn and Se, and the correlation coefficients were 0.9959, 0.9298, - 0.5728, - 0.8308 and - 0.6533, respectively（P 〈 0.05）. Conclusions The relationship between detection rate of children＇s dental fluorosis and the content of F, Cd, Cu, Zn and Se in topsoil was positively or negatively correlated in Fengjie and Wushan Counties. And the relationship between these elements and endemic fluorosis should be further studied.

关 键 词：氟中毒 牙 土壤 元素 生态学 

分 类 号：R599[医药卫生—内科学]