藏族冠心病患者临床及冠状动脉造影特征  

Characteristics of clinical data and coronary artery angiography in Tibetan coronary heart disease population

作　　者：陈仕迅[1] 陈彬[1] 李景华[1] 覃容宾[1] 王璇[1] 刘启亮[1] 

机构地区：[1]西藏军区总医院心内科,拉萨850007

出　　处：《第二军医大学学报》2013年第5期569-572,共4页Academic Journal of Second Military Medical University

摘　　要：目的探讨西藏高原地区藏族冠心病患者的临床及冠状动脉造影影像学特征。方法将2006年9月至2011年10月间在我院接受冠状动脉造影并确诊为冠心病的117例患者分为藏族组(76例,65%)和汉族组(41例,35%),收集入院后患者的血压、血糖、血脂、血尿酸等临床资料和冠状动脉造影资料,对两组患者进行对比,回顾性分析藏族冠心病患者的临床特征及冠状动脉造影的病变特点。结果在体质指数、是否合并高血压病、是否吸烟及空腹血糖、三酰甘油、总胆固醇、低密度脂蛋白胆固醇水平等方面,藏族组与汉族组差异无统计学意义(P>0.05)。但在发病年龄、高密度脂蛋白胆固醇水平及血尿酸水平方面,藏族组与汉族组差异有统计学意义(P<0.05)。藏族组的冠状动脉病变以单支病变为主,但复杂病变(三支病变、慢性闭塞性病变、C型病变)比例较大。藏族组冠状动脉病变特征分布与汉族组比较差异无统计学意义(P>0.05)。结论在西藏高原地区,高尿酸血症对藏族冠心病患者的发病有着重要意义,冠状动脉病变复杂、病情较重。Objective To explore the clinical characteristics and coronary angiography findings of Tibetan patients with coronary heart disease living in Tibetan plateau area. Methods A total of 117 eases who underwent coronary angiography and were finally diagnosed as coronary heart disease in our hospital were included in this study from September 2006 to October 2011, and they were divided into Tibetan group （76 eases, 65%） and Han group （41 cases, 35%）. The clinical data including blood pressure, glucose, blood lipids, blood uric acid and coronary angiography findings were collected and compared. The characteristics of clinical data and coronary angiography of Tibetan group were analyzed. Results There were no signi}icant differences in body mass index, fasting glucose, triglycerides, total cholesterol, low-density lipoprotein cholesterol levels, hypertension, or smoking between the two groups （P〉0.05）. The onset age, high-density lipoprotein cholesterol and uric acid levels in the Tibetan group was significantly higher than those in the Han group （P〈0. 05）. Single-vessel disease was the dominant type in the Tibetan group, but it also had a larger proportion of complex lesions （three-vessel disease, chronic occlusive lesions, and lesions C）. The coronary lesion characteristics were not significantly different between the two groups （P〉0.05）. Conclusion Hyperuricemia is of great significance for the Tibetan patients with coronary heart disease living in Tibetan plateau area, and the coronary lesions are complex and severe among them.

关 键 词：高海拔 冠心病 危险因素 冠状血管造影术 

分 类 号：R541.4[医药卫生—心血管疾病]