养心通脉消痹汤治疗气虚痰瘀互结型胸痹心痛  

Clinical Observation of Yangxin Tongmai Xiaobi Decoction on Chest Stuffiness and Pains with Syndrome of Qi Deficiency and Combined Stasis of Phlegm and Blood

作　　者：高征[1] 付伟[1] 张翠月[2] 

机构地区：[1]河南省南阳医学高等专科学校,河南南阳473006 [2]河南省南阳理工学院张仲景国医学院,河南南阳473004

出　　处：《中国实验方剂学杂志》2013年第11期296-299,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:研究养心通脉消痹汤治疗气虚痰瘀互结型胸痹心痛的临床疗效及安全性。方法:采取前瞻性研究法将64例患者随机分为治疗组、对照组。治疗组32例,以自拟养心通脉消痹汤治疗;对照组32例,用保心宁胶囊治疗。观察两组治疗前后的中医总体症状、心电图变化情况及不良反应。两组疗程均为4周。结果:治疗组、对照组总有效率分别为90.7%,78.1%,治疗后两组患者临床主要症状和心电图情况总积分均较治疗前明显下降,差异有统计学意义(P<0.05)。从血、尿常规,肝肾功等方面观察均未发现异常或不良反应。结论:养心通脉消痹汤治疗气虚痰瘀互结型胸痹心痛疗效确切,安全可靠。Objective： To observe the effect and the safety of Yangxin Tongmai Xiaobi decoction （YTXD） on chest stuffiness and pains with syndrome of qi deficiency and combined stasis of phlegm and blood. Method： Using prospective study method, 64 patients with chest stuffiness and pains were divided into two groups randomly： the treated group and the controlled group （n=32 each）. The former was given self-designed YTXD and the later was given Baoxinning capsule. The period of treatment was 4 months. Items such as symptoms, electrocardiogram, and adverse reactions were examined before treatment and after treatment. Result： The total efficacy rate in the treated group was 90.7%, the rate of the controlled group was 78.1%. Primary symptoms and total integral of electrocardiogram after the treatment of both groups were significantly reduced （P〈0.05）. No adverse reaction was found on routine blood test, routine urine test, and liver and kidney function test. Conclusion： YTXD is safe and reliable for treating chest stuffiness and pains with syndrome of Qi deficiency and combined stasis of phlegm and blood.

关 键 词：养心通脉消痹汤 胸痹心痛 气虚痰瘀互结证 

分 类 号：R287[医药卫生—中药学]