疏肝健脾和胃法治疗功能性消化不良(肝胃不和证)的临床研究  

Treating Functional Dyspepsia ( Symptoms of Disharmony between Liver and Stomach) by Smoothing the Liver and Fortifying the Spleen and Harmonizing the Stomach

作　　者：雷良蓉[1] 朱海豫 沈瑞芳[1] 

机构地区：[1]随州职业技术学院保健中心,湖北随州441300 [2]随州市曾都医院消化内科,湖北随州441300

出　　处：《中国实验方剂学杂志》2013年第11期302-305,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨疏肝健脾和胃法治疗功能性消化不良(FD)(肝胃不和证)的临床疗效。方法:86例FD患者随机分为观察组和对照组各43例。对照组采用多潘立酮片10 mg,3次/d,饭前0.5 h口服;上腹部疼痛或烧灼感者,加奥美拉唑肠溶片20 mg,1次/d,饭前半小时口服。观察组采用疏肝健脾和胃法治疗。疗程均为4周。观察肝胃不和症状,并评价生活质量。结果:观察组总有效率为90.7%,优于对照组的72.1%(P<0.05);观察组中医证候疗效总有效率为93.02%,优于对照组的67.44%(P<0.01);治疗后观察组腹胀、早饱感、上腹痛、上腹烧灼感积分及肝胃不和证候评分均明显低于对照组(P<0.01);治疗后观察组躯干功能(PF)、总体健康(GH)、情感职能(RE)、社会功能(SF)、身体疼痛(BF)及精神健康(MH)评分均高于对照组(P<0.05)。结论:疏肝健脾和胃法能明显改善功能性消化不良(肝胃不和证)的临床症状,改善患者生活质量,提高临床疗效。Objective： To investigate the clinical effect of treating functional dyspepsia （symptoms of disharmony between liver and stomach） by the method of smoothing the liver and fortifying the spleen and harmonizing the stomach. Method： Eighty-six patients with functional dyspepsia were randomly divided into the observation group and the control group with 43 cases in each group. domperidone 10 mg was taken orally 0.5 h before dinner three times per day for the control group and omeprazole enteric-coated tablets 10 mg was taken orally 0.5 h before dinner one times per day to the patients who had epigastric pain and burning. Method of smoothing the liver and fortifying the spleen and harmonizing the stomach was used to treat the observation group. The courses of two groups were both four weeks. The symptoms of disharmony between liver-stomach and evaluate the quality of life of the patients were observed. Result： The total effective rate of the observation group （90.7%） was better than that （72.1%） of the control group （P〈0.05）. The total effective rate for syndromes of traditional Chinese medicine in observation group （93.02%） was better than that （67.44%） in the control group （P〈0.01）. Scores of the syndrome of abdominal distension, early satiety, abdominal pain, epigastric burning sensation and disharmony between liver-stomach after treatment in the observation group were significantly lower than those in the control group （P〈0.01）. Scores of the trunk function （PF）, general health （GH）, role emotional （RE）, social function （SF）, bodily pain （BF） and mental health （MH） after treatment in the observation group were higher than those in the control group （P〈0.05）. Conclusion： The treatment of smoothing the liver, fortifying the spleen and harmonizing the stomach can significantly improve the clinical symptoms of functional dyspepsia, the quality of life and the clinical efficacy.

关 键 词：功能性消化不良 肝胃不和证 疏肝健脾和胃法 生活质量 

分 类 号：R287[医药卫生—中药学]