术中知晓的研究进展  

Research Progress in Intraoperative Awareness

作　　者：王倩[1] 郝在军[2] 敖虎山[3] 王志发[2] 

机构地区：[1]内蒙古医科大学研究生学院,呼和浩特010000 [2]内蒙古医科大学鄂尔多斯临床医学院,内蒙古鄂尔多斯017000 [3]北京市阜外心血管病医院,北京100037

出　　处：《医学综述》2013年第10期1811-1813,共3页Medical Recapitulate

摘　　要：术中知晓是指患者在全身麻醉手术中存在意识和明确的记忆,是全身麻醉的并发症之一。其中,意识由皮质下介导的大脑觉醒和由丘脑皮质系统介导的主观体验构成,记忆由内隐记忆(无意识记忆)和外显记忆(有意识记忆)构成。其中,具有外显记忆的术中知晓是患者和麻醉医师共同关心的问题,其可能会导致严重的心理后遗症,如创伤后应激障碍。该文就术中知晓的神经生物学机制、国内外发生率、可能的危险因素及预防措施等予以综述。Intraoperative awareness is defined as a condition at which patients have both consciousness and explicit memory during surgical operation under general anesthesia,and it is one of the general anesthesia complications.The consciousness is made up of the brain awareness mediated by subcortex and the subjective experience mediated by thalamocortical system;the memory is made up of implicit（unconscious） memory and explicit（conscious） memory.The awareness with explicit memory is a common issue for patients and anesthetists to care for,since it can lead to serious psychological sequelae,like posttraumatic stress disorder.Here is to make a review of the neurobiology,the incidence in China and abroad,the possible risk factors and the preventive measures of intraoperative awareness.

关 键 词：术中知晓 全身麻醉 神经生物学机制 

分 类 号：R614[医药卫生—麻醉学]