卵巢过度刺激综合征并发深静脉血栓临床研究并文献复习  

Clinical Research of Ovarian Hyperstimulation Syndrome Complicated with Deep Vein Thrombosis and Review of the Literature

作　　者：光晓燕[1] 于琳[1] 李璟[1] 

机构地区：[1]北京大学深圳医院妇产科,深圳518036

出　　处：《医学综述》2013年第10期1910-1912,共3页Medical Recapitulate

摘　　要：目的分析卵巢过度刺激综合征(OHSS)并发深静脉血栓(DVT)的临床特征、诊疗方法及预防措施,以提高临床医师对该疾病的认识。方法回顾性分析北京大学深圳医院收治的2例OHSS并发DVT的临床资料,并检索相关文献,总结诊治经验。结果国内外文献报道OHSS并发DVT 31例,27例报道其发病与辅助生殖技术(ART)有关,所有患者均使用低分子肝素治疗,效果良好,合并妊娠者可获得良好的妊娠结局。栓塞部位多发于上肢头颈部位。结论 OHSS并发DVT是ART相关的致命性并发症,虽然低分子肝素治疗有效,但积极预防OHSS发生是减少血栓发病的关键,对于高危人群尤其要提高警惕,必要时可进行易栓症筛查。Objective To analyze the clinical features,diagnosis,treatments and precautions of ovarian hyperstimulation syndrome（OHSS） complicated with deep vein thrombosis（DVT）,to improve the recognition of the disease of the clinicians.Methods Two cases of OHSS with DVT in Peking University Shenzhen Hospital were retrospectively analyzed and the related literature was reviewed.The diagnosis and treatment experiences were summarized.Results Thimty-one cases of OHSS with DVT were reported in the literature.27 cases were closely related to assisted reproductive techniques（ART）.Anticoagulation with low molecular weight heparin was beneficial and pregnant women could get good outcome.The site of embolization was predominantly in the upper extremity,head and neck.Conclusion OHSS with DVT was a serious consequence of ART.Although the low molecular weight heparin is effective,active prevention of OHSS is critical to reduce the incidence of thrombosis.Those patients with personal or familial history should be be paid more attention to,screening should be done if necessary.

关 键 词：卵巢过度刺激综合征 深静脉血栓 辅助生殖技术 低分子肝素 

分 类 号：R711[医药卫生—妇产科学]