小球藻多糖体外免疫调节活性研究  

Immunomodulation Activities in vitro of Polysaccharides from Chlorella sp.

作　　者：王凌[1] 孙利芹[1] 周妍[1] 

机构地区：[1]烟台大学生命科学学院,山东烟台264005

出　　处：《食品研究与开发》2013年第7期30-33,共4页Food Research and Development

基　　金：山东省自然科学基金(Y2007D59);烟台市科技发展计划(2009219)

摘　　要：通过考察小球藻多糖对小鼠脾脏淋巴细胞增殖,腹腔巨噬细胞增殖、吞噬中性红、释放NO能力的,研究了小球藻多糖对小鼠体外免疫细胞功能的影响。结果显示,小球藻多糖可增强吞噬细胞的吞噬功能,促进巨噬细胞合成NO,促进脾淋巴细胞及腹腔巨噬细胞的增殖。表明小球藻多糖具有增强小鼠细胞免疫功能的作用。In order to study the effects of Chlorella polysaccharides on immunocell functions of mice, the immunomodulatory activities of polysaccharides from Chlorella sp were evaluated by Splenocyte proliferation, peritoneal macrophage activation, neutral red uptake by Raw264.7 cell and NO emission detection in vitro. The results showed that the Chlorella polysaceharides could enhance the immunologic function of healthy mice. The polysaecharide enhanced the phagocytic activity of neutral red, increased nitro oxide （NO） production, stimulated spleen lymphocyte proliferation and macrophage proliferation obviously.

关 键 词：小球藻 多糖 免疫调节 生物活性 

分 类 号：R285.5[医药卫生—中药学]