胸腔置管引流在恶性胸水中的临床应用  

Clinical application of thoracic cavity drainage in treatment of malignant hydrothorax

作　　者：史恩红[1] 张东利[1] 石丽欣[1] 

机构地区：[1]黑龙江省医院,黑龙江哈尔滨150036

出　　处：《中国校医》2013年第5期376-377,共2页Chinese Journal of School Doctor

摘　　要：目的对晚期肿瘤胸水患者采用胸腔置管引净积液后灌注化疗药物或生物制剂,并观察其疗效及不良反应。方法随机将恶性胸水患者分成两组,分别采用置管引流及胸腔穿刺抽水后灌注药物。结果治疗组15例,有效率80%,对照组15例,有效率53.3%(P<0.05);患者机能状况KPS评分改善治疗组优于对照组(P<0.05)。结论导管型抽液器行置管引流术加局部药物灌注治疗效果明显优于传统穿刺术且安全性高。Objective To evaluate the therapeutic effects and adverse reactions of infusing chemotherapeutic drugs or biological agents into the pleural cavity of the patients with advanced tumors by means of pleural cavity drainage. Methods The patients with malignant pleural effusion were randomly divided into two groups. The pleural cavity drainage and thoracentesis were operated respectively. Results The response rate of 15 cases of the treatment group was 80 %, whereas the response rate of the 15 cases of the control group was 53.3 % （ P 〈 0.05）. The improvement of Karnofsky performance status （KPS） in the treatment group was more than that in the control group （P 〈 0.05）. Conclusions The effect of infusing drugs into the pleural cavity by means of pleural cavity drainage is superior to thoracentesis and the operation of pleura[ cavity drainage is safer than thoracentesis.

关 键 词：胸腔积液 恶性 引流术 胸管 

分 类 号：R655.1[医药卫生—外科学]