预阳极化碳糊电极同时测定对乙酰氨基酚和多巴胺  

The simultaneous determination of acetaminophen and dopamine at a pre-anodized carbon paste electrode

作　　者：孙瑶[1] 上官恩波[1] 李晶[1] 李全民[1] 

机构地区：[1]河南师范大学化学化工学院,新乡453007

出　　处：《分析试验室》2013年第6期59-62,共4页Chinese Journal of Analysis Laboratory

基　　金：河南省教育厅自然科学基金(2008B150011)资助

摘　　要：采用循环伏安法制备了预阳极化碳糊电极,研究了对乙酰氨基酚和多巴胺在该修饰电极上的电化学行为。结果表明,预阳极化碳糊电极对对乙酰氨基酚和多巴胺的电化学行为具有良好的电催化作用。对乙酰氨基酚和多巴胺的氧化峰电流与其浓度在2.0×10-6～5.0×10-4mol/L的范围内呈良好的线性关系,检出限分别为6.3×10-7mol/L,2.5×10-7mol/L。方法已用于药物样品中对乙酰氨基酚和多巴胺的测定。A pre-anodized carbon paste electrode was prepared by cyclic vohammetry. The electrochemical behaviors of acetaminophen and dopamine were investigated on the modified electrode. The experimental results showed that the electrode had excellent electrocatalytic activity to acetaminophen and dopamine. The oxidation peak currents were proportional to the concentrations of acetaminophen and dopamine both in the range of 2. 0×104 -5.0×10^4mol/L, and the detection limits were 6. 3×10^-7mol/L and 2. 5×10^-7mol/L, respectively. The proposed method was applied to the determination of acetaminophen and dopamine in commercial pharmaceutical samples with satisfactory results.

关 键 词：预阳极化碳糊电极 对乙酰氨基酚 多巴胺 

分 类 号：O657.1[理学—分析化学]