小剂量托特罗定治疗小儿遗尿症的临床疗效  

The curative effect of small dose Tolterodine in the treatment of primary nocturnal enuresis

作　　者：宫小勇[1] 杜红[1] 薛亚辉[1] 郑伟[1] 孙小敏[1] 

机构地区：[1]陕西中医学院第二附属医院泌尿外科,陕西咸阳712000

出　　处：《现代泌尿外科杂志》2013年第3期265-267,共3页Journal of Modern Urology

摘　　要：目的探讨小剂量托特罗定治疗小儿遗尿症的疗效。方法2008年6月至2012年5月,对125例被诊断为小儿遗尿症的患儿进行随机对照研究,设置空白对照组、治疗组(口服小剂量托特罗定)。以夜间遗尿次数作为主要疗效指标。治疗3个月、停药1月后的下1周进行疗效评价。结果治疗后治疗组遗尿≥2次/周的人数由69例下降为17例,对照组由56例下降为52例。治疗组下降率(75.36%)明显高于对照组(7.14%)(P<0.005),无严重副反应。结论小剂量托特罗定用于治疗小儿遗尿症有较好疗效和安全性。Objective To explore the curative effect of small dose Tolterodine to treat primary nocturnal enuresis. Methods From June 2008 to May 2012, 125 cases diagnosed as primary nocturnal enuresis were randomized into the control group and treatment group. The treatment group took small dose tolterodine tartrate tablets orally for 3 months. Night enuresis times was taken as index to evaluate the curative effect. 5 weeks after the treatment, the curative effect was evaluated. Results The number of primary nocturnal enuresis cases dropped from 69 to 17 in the treatment group, and dropped from 56 to 52 in the control group. There was significant difference between the two groups （P〈 0. 005）. Conclusion Small dose of tolterodine is safe and effective in the treatment of primary nocturnal enuresis.

关 键 词：托特罗定 遗尿症 小儿 

分 类 号：R694.53[医药卫生—泌尿科学]