健脾祛风方治疗脾虚型特应性皮炎临床疗效评价  

Clinical Efficacy of Strengthening Spleen and Expelling Wind Decoction on Atopic Dermatitis Syndrome Identified as Spleen Asthenia

作　　者：彭勇[1] 李斌[2] 王英杰[1] 武宗琴 柴维汉 

机构地区：[1]上海市嘉定区中医医院,上海201800 [2]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《中医药导报》2013年第5期11-13,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：上海市卫生局中医药科研基金(2010L081A)

摘　　要：目的:探讨健脾祛风方治疗脾虚型特应性皮炎的临床疗效及其对血清总IgE、嗜酸性粒细胞计数的影响。方法:将符合纳入标准的特应性皮炎患者192例随机分为治疗组95例和对照组97例,治疗组予自拟健脾祛风方、尿素乳膏治疗,对照组予西替利嗪片、尿素乳膏治疗,治疗4周后比较两组疗效及其实验室指标。结论:总有效率治疗组为82.1%,对照组为61.9%,治疗组优于对照组,差异有统计学意义(P<0.05);两组治疗后血清总IgE、嗜酸性粒细胞(EOS)计数均较治疗前降低(P<0.05);治疗后两组血清总IgE、嗜酸性粒细胞(EOS)计数比较,治疗组低于对照组(P<0.05)。结果:健脾祛风方治疗脾虚型特应性皮炎疗效确切。Objective： To explore the therapeutic effects of Strengthening Spleen and Expelling Wind decoction for the spleen-deficiency atopic dermatitis （AD）,and to investigate the transformation of IgE and EOS. Methods： 192 patients meeting the inclusion criteria were randomly divided into treatment group （95 cases） and control group （97 cases）. Patients were treated by Strengthening Spleen and Expelling Wind Decoction and Urea Ointment in treatment group, cetirizine hydrochloride tablets and Urea Ointment in control group. The therapeutic effect and laboratory indexes were observed in 4 weeks. Results： The total effective rate was 82.1% and 61.9% respectively in treatment and control groups, and the clinical effect in the treatment group was better than that of the control group, with significant difference （P〈0.05）;the IgE and EOS decreased in both treatment and control groups （P〈0.05）; the IgE and EOS in treatment group were lower than that of the control group after treatment （P〈0.05）. Conclusion： Strengthening Spleen and Expelling Wind Decoction can provide indubitable effect for AD, which isi dentified as Spleen Asthenia.

关 键 词：自拟健脾祛风方 脾虚证 特应性皮炎 

分 类 号：R275[医药卫生—中医皮科]