一种色氨酸修饰的香豆素类Cu^(2+)荧光探针的合成及性能研究  

Synthesis and Properties of a Fluorescent Probe Based on Tryptophan Modified Coumarin for Copper (Ⅱ) Ion

作　　者：张敏[1] 杨丽庭[1] 刘佳伦[1] 谢婉利[1] 蒙旭亮[1] 马立军[1] 

机构地区：[1]华南师范大学化学与环境学院,广东广州510006

出　　处：《华南师范大学学报（自然科学版）》2013年第3期59-62,共4页Journal of South China Normal University(Natural Science Edition)

基　　金：国家自然科学基金项目(20903041);广州市珠江科技新星项目(2012J2200026)

摘　　要：合成了一种色氨酸修饰的香豆素类荧光探针——香豆素色氨酸甲酯,它以色氨酸基团作为金属离子的识别位点、以香豆素基团作为荧光信号基团.结果表明:在水溶液中该探针能够对Cu2+表现出荧光猝灭效应,而相同测试条件下其他重金属离子的加入对探针的荧光发射没有影响,因此该探针对Cu2+可选择性识别.A new fluorescence probe was synthesized： coumarin-tryptophan-ester （CTE）, using tryptophan as a recognition group to heavy metal ion and rhodamine as the fluorescence signal groups. The experiment results indicated that the probe showed a specific selective recognition for Cu2＋ in aqueous solution with a fluorescent quenching signal. No obvious fluorescence changes were observed for CTE in the presence of other metal ions at the same concentration. Therefore, the fluorescence probe showed a selective recognition to Cu2＋.

关 键 词：CU2+ 荧光探针 色氨酸 香豆素 

分 类 号：O629.71[理学—有机化学]