超声强化苯甲醛接枝壳聚糖的缩合反应  

Ultrasonic-assisted condensation of chitosan with benzaldehyde

作　　者：段丽红[1,2] 吴正治[1] 郭祀远[2] 陈利国[3] 

机构地区：[1]暨南大学第二临床医学院,广东深圳518020 [2]华南理工大学轻工与食品学院,广东广州510641 [3]暨南大学医学院,广东广州510632

出　　处：《陕西科技大学学报（自然科学版）》2013年第3期77-80,92,共5页Journal of Shaanxi University of Science & Technology

基　　金：国家863高技术研究发展计划项目(2007AA100405);高等学校博士学科点专项科研基金项目(20050561014);广东省教育厅产学研结合项目(2008B090500002)

摘　　要：壳聚糖希夫碱具有优良的金属离子螯合能力,但传统方法制备的反应时间长,缩合率不高。为了缩短制备的时间和提高缩合率.本文引入超声场来强化该缩合反应,并通过正交设计实验优化反应条件.超声辅助反应的缩合度为92.99%,比传统方法提高了19.03%;超声辅助制备的优化条件为:反应物配比(n苯甲醛∶n壳聚糖)为6,超声功率为180kW,超声处理时间为4h,反应温度为70℃,反应溶液pH为5.Schiff bases of chitosan have excellent metal ion chelating ability, but reaction time is long, and the condensation degree is low when prepared by traditional method. In order to shorten the reaction time of the condensation reaction of chitosan with benzaldehyde and im- prove the condensation rate. Ultrasonic field was introduced to strengthen the condensation reaction, and the reaction conditions were optimized by orthogonal design experiment. A con- densation degree of 92.99% which was more 19.03% than that of traditional method was a- chieved using the optimized conditions： i.e. ultrasonic irradiation at 180 W for 4 h,pH 5.0, and benzaldehyde ： chitosan ratio of 6 ： 1.

关 键 词：壳聚糖 苯甲醛 超声场 

分 类 号：O621.25[理学—有机化学]