蠕虫感染影响过敏性哮喘的免疫学机制  

Effects of helminth infections on the mechanisms of immune response in allergic asthma

作　　者：马萍[1] 于剑 王成艳[3] 闫玉文[1] 

机构地区：[1]武警后勤学院病原生物与免疫学教研室,天津300162 [2]山东总队医院肿瘤科 [3]武警后勤学院中心实验室

出　　处：《中国病原生物学杂志》2013年第5期476-478,I0002,共4页Journal of Pathogen Biology

摘　　要：虽然有关蠕虫感染对过敏性哮喘的影响已有一些研究成果,但结论不尽相同。寄生虫的虫种、感染时间、感染强度、抗感染治疗的时间,甚至宿主的遗传背景等因素都可以影响二者的关系。现今,对蠕虫感染影响过敏性哮喘的免疫学机制研究较多的是调节性T细胞、树突状细胞及IL-10等多种免疫细胞和细胞因子。Although some studies have explored the interaction between asthma and helminth infections, their conclusions differ. The relationship between worm infections and the development of allergic asthma may depend on several factors, including the worm species, the timing of infection, intensity of infection, and the host＇s genetic characteristics. Recent studies seeking to determine the effects of helminth infections on the development of asthma have focused mainly on immune cells and cytokines including regulatory T cells, dendritic cells, and IL-10.

关 键 词：蠕虫感染 过敏性哮喘 调节性T细胞 树突状细胞 综述 

分 类 号：R383[医药卫生—医学寄生虫学]