冠心病患者中心动脉压与肱踝脉搏波速度的相关性研究  

Research of relation between central artery pressure and brachial-ankle pulse wave velocity in patients with coronary artery disease

作　　者：闫博宇[1,2] 张英[2] 陈予新 王春雨[2] 郑力[2] 章隽[2] 石浩[2] 任菁[2] 赵敬敏[2] 高永红[2] 

机构地区：[1]遵义医学院 [2]北京航天总医院,联合培养研究生563003

出　　处：《中国现代医药杂志》2013年第5期12-14,共3页Modern Medicine Journal of China

摘　　要：目的探讨冠心病患者中心动脉压(CAP)与肱-踝脉搏波速度(baPWV)的相关性。方法选择冠状动脉造影(CAG)检查患者100例,按冠心病诊断标准分为冠心病组65例,非冠心病组35例。记录血管造影过程中检测到的升主动脉压力作为CAP,并采用全自动动脉硬化检测仪测定baPWV。结果①冠心病组较非冠心病组CSP、baPWV、TC、LDL-C水平有统计学差异(P<0.05)。②多元线性逐步回归分析显示年龄、CSP、CDP、FBG和LDL-C是baPWV的独立影响因素。结论冠心病患者CAP升高,进一步促进了主动脉管壁弹性下降,中心动脉僵硬度增高,而年龄、中心动脉压、FBG、LDL-C是影响动脉僵硬度的独立危险因素。Objective To study the relation of central artery pressure （CAP） and brachial-ankle pulse wave velocity （baPWV） in patients with coronary artery disease （CAD）. Methods One hundred patients who underwent coronary angiogra- phy （CAG） were subjected and divided into CAD group（n=65）, and control group（n=35）. Central aortic pressure was invasive- ly determined by catheterization and baPWV was measured with a PWV device. Results （~）The central artery systolic pressure （CSP）, TC, LDL-C and baPWV were significandy higher in CAD group than that in control group （P〈0.05）. （~）Muhiple linear regression analysis showed that age, CSP,CDP, FBG and LDI-C were the independent risk factors for baPWV. Conclusion The central artery pressure is significantly higher in patients with CAD, promoting further artery elasticity decrease. Age, CAP, FBG and LDL-C are the independent risk factors for arterial stiffness.

关 键 词：中心动脉压 冠心病 动脉硬化 肱-踝脉搏波速度 

分 类 号：R541.4[医药卫生—心血管疾病]