大孔吸附树脂与离子交换树脂联用分离富集复方肝康片中总黄酮与总生物碱的工艺研究  

Study on Separation and Enriching Total Flavonoids and Total Alkaloids in Compound Gankang Tablet by Macroporous Adsorption Resin and Ion Exchange Resins

作　　者：胡婧文[1] 王琼[1] 狄留庆[1,2,3] 

机构地区：[1]南京中医药大学药学院,江苏南京210023 [2]江苏省中药高效给药系统工程技术研究中心,江苏南京210023 [3]南京市中药微丸产业化工程技术研究中心,江苏南京210023

出　　处：《南京中医药大学学报》2013年第3期266-270,共5页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家自然科学基金(81073071);江苏省"青蓝工程"科技创新团队支持计划[苏教师(2008)30号];江苏省优势学科建设工程资助项目(ysxk-2010)

摘　　要：目的分离富集复方肝康片中总黄酮与总生物碱。方法联合应用大孔吸附树脂与钠型阳离子树脂分别对处方中的总黄酮与总生物碱进行分离,并对工艺进行验证。结果联合应用大孔吸附树脂与钠型阳离子树脂可较好地分离富集复方中总黄酮与总生物碱。结论联合应用大孔吸附树脂和钠型阳离子树脂分离复方肝康片中总黄酮和总生物碱的方法可行。OBJECTIVE To separate and enrich the total flavonoids and total alkaloids from compound Gankang tablet. METHODS Combined applying macroporous resin and sodium cation resin to separate the total flavonoids and the total alka- loids respectively from the prescription, then verify the process. RESULTS Combination macroporous resin and sodium cation resin contributed to separate and enrich total flavonoids and total alkaloids. CONCLUSION It was feasible to use macroporous resin and sodium cation resin to separate total flavonoids and total alkaloids from compound Gankang tablet.

关 键 词：大孔吸附树脂 钠型阳离子树脂 总黄酮 总生物碱 分离 富集 

分 类 号：R284.2[医药卫生—中药学]