沙美特罗替卡松联合金水宝胶囊治疗中度非急性发作期支气管哮喘100例临床观察  

Observation on Salmeterol Fluticasone Combined with JinShuiBao Capsule for 100 Cases of Moderate Bronchial Asthma during the Period of Non Acute Attack

作　　者：向建华[1] 毛良平[1] 韩鹏凯[1] 王世波[1] 张锦聪[2] 

机构地区：[1]重庆三峡中心医院,重庆万州404000 [2]甘肃中医学院

出　　处：《西部中医药》2013年第5期97-99,共3页Western Journal of Traditional Chinese Medicine

基　　金：2012年万州区第二批科技计划项目(编号201203052)

摘　　要：目的:观察沙美特罗替卡松联合金水宝胶囊治疗中度非急性发作期支气管哮喘的临床疗效及不良反应。方法:将200例患者随机分为2组。试验组100例采用沙美特罗替卡松(50μg/250μg)联合金水宝胶囊治疗;对照组100例单用沙美特罗替卡松(50μg/250μg)治疗。治疗6个月、12个月后观察2组哮喘控制水平(FEVl)改善情况、哮喘控制测试ACT评分情况及咽部不适发生率、声音嘶哑发生率、咽部真菌感染发生率。结果:试验组在FEVl改善、哮喘控制测试ACT评分方面明显优于对照组(P<0.05);在不良反应(咽部不适、声音嘶哑、咽部真菌感染)方面明显少于对照组(P<0.05)。结论:沙美特罗替卡松联合金水宝胶囊对中度非急性发作期支气管哮喘控制良好,不良反应少。Objective： To verify clinical effects and adverse reaction of salmeterol fluticasone combined with JinShuiBao capsule for moderate bronchial asthma during the period of non acute attack. Method： All 200 patients were randomized into two groups. The patients of the experiment group were administered with salmeterol fluticas- one （50 μg/250μg） combined with JinShuiBao capsule; 100 eases of the control group received salmeterol fluticas- one（50 μg/250μg） only. The incidence of pharyngeal mycotic infection, hoarseness, pharyngeal discomfort, the scores of asthma control test （ACT） and the improvement of asthma control level were observed after treating for six months and one year. Result： The experiment group was superior to the control group in the improvement of asthma control level and the scores of ACT （P〈0.05）; less than the control group in adverse reactions （pharyngeal discom- fort, hoarseness and pharyngeal mycotic infection） （P〈0.05）. Conclusion： Salmeterol fluticasone combined with Jin- ShuiBao capsule could control moderate bronchial asthma during the period of non acute attack well with minor ad- verse reaction.

关 键 词：支气管哮喘 沙美特罗替卡松 金水宝胶囊 

分 类 号：R562.2[医药卫生—呼吸系统]