痹痛巴布剂质量标准的研究  

Study on the Quality specification of Bitong Cataplasm

作　　者：罗霄山[1] 孙冬梅[2] 罗文汇[2] 胥爱丽[2] 李素梅[2] 

机构地区：[1]广东省第二中医院,广州510095 [2]广东省中医研究所,广州510095

出　　处：《海峡药学》2013年第4期8-10,共3页Strait Pharmaceutical Journal

基　　金：广东省科技计划项目(项目编号:2010B030700022)

摘　　要：目的建立痹痛巴布剂的质量标准。方法采用薄层色谱法对方中续断、桑寄生、两面针和附子等四味药进行了薄层色谱鉴别;采用高效液相法测定了桂枝中桂皮醛的含量。结果薄层色谱斑点清晰,阴性对照无干扰;桂皮醛在7.828～78.280ng范围内呈线性关系(r=0.99992),平均回收率为98.35%,RSD(n=6)为0.52%。结论该方法可有效地控制痹痛巴布剂的质量。OBJECTIVE To establish the quality specification of Bitong Cataplasm.METHODS The TLC methods were used to identify Dipsaci Radix,Taxilli Herba,Zanthoxyli Radix and Aconiti Lateralis Radix Praeparata.The content of Cinnamaldehyde in Bitong Cataplasm was determined by HPLC.RESULTS The TLC spots were fairly clear and the blank test showed no interference.The calibration curves were linear in the range of 7.828-78.280ng（r=0.99992） for imperatorin.The average recovery（n=6） was 98.35% and with RSD 0.52%.CONCLUSION This method could control the quality of Bitong Cataplasm effectively.

关 键 词：痹痛巴布剂 质量标准 桂皮醛 高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]