环己醇合成工艺的改进  

Improvement of synthesis of cyclohexanol

作　　者：孔祥文[1] 邱锦锋[1] 

机构地区：[1]沈阳化工大学应用化学学院,辽宁沈阳110142

出　　处：《实验技术与管理》2013年第5期17-18,21,共3页Experimental Technology and Management

基　　金：辽宁省教育科学"十一五"规划立项课题高校精品课程建设的理论与实践研究(JG09DB112);辽宁省教育厅高等学校科学研究项目(202092009)

摘　　要：以环己烯为起始原料,两步法合成环己醇。对环己醇合成的关键步骤———氧化反应的氧化剂进行了改进,考察了合成反应的诸多因素。最佳工艺条件是:硼氢化反应中,浓度比n(硼氢化钠)∶n(三氟化硼)∶n(环己烯)=1.0∶1.05∶1.0,三氟化硼滴加时间30min;氧化反应中,氧化反应温度(40℃±2℃),反应时间60min。工艺经改进后,产物的收率达到91.4%。As an important organic chemical material, cyclohexanol is widely used in preparation of adipic acid and caprolactam. Cyclohexanol is synthesized from cyclohexene as raw material by two-step reactions. The oxdiant in the key step of oxidation reaction is improved. The influence of some factors on the synthesis process is studied. The optimal reaction conditions are chosen that the molar ratio of sodium borohydride and boron trifluoride and cyclohexene is 1.0 ：1.05 ： 1.0, the dropping addition of boron trifluoride is 30 min for the hydroboration; the reaction temperature is （40 ℃±2℃）, the reaction time is 60 min for the oxidation reaction. Under the optimal reaction conditions, the yield of cyclohexanol could reached a level of 91.4%,which is 9.8% higher than before.

关 键 词：环己醇 环己烯 合成工艺 硼氢化 

分 类 号：O624.333[理学—有机化学]