加强可引起QT间期延长和尖端扭转型室速药物的处方审核  

Verification of the prescriptions caused the drug-induced QT prolongation and torsade de pointes

作　　者：赵永红[1] 沈德莉[1] 

机构地区：[1]复旦大学附属华山医院静安分院药剂科,上海200040

出　　处：《世界临床药物》2013年第5期316-319,共4页World Clinical Drug

摘　　要：临床应加强对可引起QT间期延长和尖端扭转型室速(TdP)的常用药物的处方审核,以便及时提出警示信息,确保用药合理有效。本文简要介绍药物引起QT间期延长及TdP的机制及相关药物,综述药源性TdP的危险因素,以及药师的处方审核方法等。Clinical pharmacists should pay more attention to verify the prescription of drugs,which can cause QT prolongation and torsade de pointes（TdP）.They also need to timely present warning information and announcements to ensure the rational and effective use of drugs.This review describes the mechanism of drug-induced QT prolongation and TdP in related drugs and discusses their risk factors and prescription verification.

关 键 词：QT间期延长 尖端扭转型室速 处方审核 

分 类 号：R969.3[医药卫生—药理学]