不同性别老年冠心病冠状动脉旁路移植术患者代谢性危险因素特征  

Characteristics of metabolic risk factors in elderly coronary heart disease patients after coronary artery bypass grafting

作　　者：包柄楠[1] 孙秀芹[1] 赵怡[1] 陶红[1] 周迎生[1] 

机构地区：[1]首都医科大学附属北京安贞医院内分泌科,100029

出　　处：《中华老年心脑血管病杂志》2013年第6期569-571,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨不同性别行冠状动脉旁路移植术(CABG)治疗的老年冠心病患者代谢性危险因素特征。方法选择老年冠心病CABG患者398例,分为男性组272例,女性组126例,比较2组患者的代谢性危险因素特征。结果女性组体重指数、收缩压、TC、HDL-C、LDL-C和TG均高于男性组(P=0.003,P=0.000),血尿酸水平低于男性组,差异有统计学意义(P=0.000)。2组的年龄、舒张压、空腹血糖、糖化血红蛋白水平比较,差异无统计学意义(P>0.05)。女性组血脂异常的比例高于男性组,吸烟的比例低于男性组(P=0.000),2组高血压、糖尿病和多支血管病变的比例比较,差异无统计学意义(P>0.05)。结论老年女性冠心病CABG患者的血脂异常和收缩压升高更为严重,吸烟比例和血尿酸水平低。Objective To study the characteristics of metabolic risk factors in elderly coronary heart disease （CHD） patients after coronary artery bypass grafting （CABG）. Methods Three hundred and ninety-eight elderly CHD patients were divided in male patients group （n=272） and female patients group （n= 126）. The characteristics of metabolic risk factors in the two groups were compared. Results The BMI,SBP,and serum TC, HDL-C, LDL-C and TG levels were sig- nificantly higher whereas the serum UA level was significantly lower in female patients group than in male patients group （P = 0. 003, P= 0. 000）. No significant difference was found in age, DBP,and fasting blood glucose and HbAlc levels between the two groups （P〉0.05）. The per- centage of dyslipidemia was higher whereas that of smoking was lower in female patients group than in male patients group （P=0. 000）. No significant difference was observed in the incidence of diabetes mellitus, hypertension and multiple vessel lesion between the two groups （P〉0.05）. Conclusion The percentage of dyslipidemia and elevated SBP is significantly higher whereas that of smoking and serum UA level is significantly lower in elderly female CHD patients than in eld- erly male CHD patients after CABG.

关 键 词：冠心病 冠状动脉旁路移植术 非体外循环 代谢疾病 血脂异常 糖尿病 性别因素 危险因素 

分 类 号：R654.2[医药卫生—外科学]