神经肌蒂移植同时恢复麻痹声带内收及外展功能的实验研究  

Recovery of the Adductive and Abductive Function of the Paralyzed Vocal Cord in Dog

作　　者：陈贤明[1] 王正强[2] 郑明秀[2] 吴平[2] 

机构地区：[1]第四军医大学西京医院耳鼻咽喉科 [2]昆明医学院第二附属医院耳鼻咽喉科,昆明650101

出　　处：《听力学及言语疾病杂志》2000年第3期146-148,共3页Journal of Audiology and Speech Pathology

基　　金：云南省教委科研基金资助项目!(编号9612112)

摘　　要：目的　探索一种能同时恢复麻痹声带内收及外展功能的治疗方法。方法　对狗一侧喉返神经及喉上神经运动支联合麻痹的喉内肌 ,采用颈袢胸骨甲状肌肌蒂移植于麻痹侧环杓后肌 ,颈袢甲状舌骨肌肌蒂移植于麻痹侧环杓侧肌作为实验组 ,并仅用颈袢胸骨甲状肌肌蒂移植于麻痹侧环杓后肌作为对照组。术前及术后 4个月行声带录像、喉肌电图检测、组织学检查。结果　术后 4个月所有动物均不同程度地恢复了麻痹声带的生理功能。实验组术侧声带内收运动明显优于对照组。所有受植喉肌均出现诱发动作电位 ,组织学检查显示受植肌获神经再支配 ,肌肉形态结构基本正常。对照组失神经支配的环杓侧肌显示肌肉萎缩、变性。结论　采用神经肌蒂移植同时恢复麻痹声带内收。Objective To pursue an effective method to recover the adductive and abductive function of the paralyzed vocal cord simultaneously.Mothods The left recurrent laryngeal nerve and superier laryngeal nerve in dogs were damaged.The ansa cervicalis sternothyroid muscular pedicles were transplanted to paralyzed posterior cricoarytenoid muscles,and ansa cervicalis thyrohyoid muscular pedicles were transplanted to paralyzed lateral cricoarytenoid muscles as the experimental group.Only ansa cervicalis sternothyroid muscular pedicles were transplanted to the paralyzed posterior cricoarytenoid muscles as the control group.Before and four months after the operation,laryngoscopy,laryngeal electronyography and histological study were undergone respectively.Results the embedded muscles were all reinnervated,the adductive and abductive functions of the paralyzed vocal cords were recovered in varying degrees,the abductive activity was superior in the experimental group to that in the control group.Laryngeal electromyography and histological appearance also supported the results.Conclusion The method of recovering the adductive and abductive functions of the paralyzed vocal cord simultaneously was available and effective.

关 键 词：声带麻痹 神经肌蒂 神经再支配 环杓后肌 

分 类 号：R767.62[医药卫生—耳鼻咽喉科]