代谢综合征对老年良性前列腺增生的影响研究  

Influence of metabolic syndrome on aged patients with benign prostatic hyperplasia

作　　者：苗莉[1] 陈哲[1] 高春英[2] 刘淼冰[2] 宁志伟[1] 王广[1] 徐援[1] 

机构地区：[1]首都医科大学附属北京朝阳医院内分泌科,100020 [2]首都医科大学附属北京朝阳医院综合科,100020

出　　处：《现代医药卫生》2013年第10期1446-1447,1450,共3页Journal of Modern Medicine & Health

摘　　要：目的初步探讨代谢综合征(MS)对老年患者良性前列腺增生(BPH)的影响。方法将154例老年BPH患者分为MS伴BPH(MS+BPH)组和单纯BPH组,比较两组患者国际前列腺症状评分(IPSS)、前列腺体积(PV)、最大尿流率(Qmax)及前列腺特异性抗原(PSA)的差别,并进一步分析MS各指标与PV的相关性。结果 MS+BPH组与单纯BPH组患者PV[(51.3±12.7 vs.44.9±11.0)mL]、IPSS[(24.6±8.9 vs.18.1±7.4)分]、PSA[(3.23±1.05 vs.1.94±1.12)μg/L]比较,差异有统计学意义(P<0.05)。PV与年龄、体质量指数(BMI)、SBP、三酰甘油(TG)、空腹血糖(FPG)及胰岛素抵抗指数(HOMA-IR)呈正相关(P<0.05),与高密度脂蛋白(HDL)呈负相关(P<0.05)。结论 BPH伴MS时PV更大,症状更重,PV与年龄、BMI、TG、FPG、HOMA-IR和HDL明显相关。Objective To investigate the influence of metabolic syndrome （MS） on elderly patients with benign prostatic hyperplasia （BPH）. Methods 154 elderly patients with BPH were divided into the MS＋BPH group and the simple BPH group. The international prostate symptom score （IPSS）, prostate volume （PV）, maximum urinary flow rate （Qmax） and prostate-specific antigen （PSA） were compared between the two groups. And further analysis of the correlation between MS indicators and PV was carried. Results The differences of PV[（51.3~12.7 vs. 44.9~11.0）mL],IPSS（24.6＋8.9 vs.18.1~7.4） ,PSA[（3.23~l.05 vs. 1.94~ 1.12 ）Ixg/L] between the BPH＋MS group and the BPH group were statistically significant （P〈0.05） ;PV was positively correlated with age, BMI, SBP, TG, FBG and HOMA-IR（P〈0.05 ）, and negatively correlated with HDL（P〈0.05 ）. Conclusion PV of the pa- tients with BPH complicating MS is larger and symptoms are heavier. PV is significantly correlated with age,BMI,TG,FPG, HOMA-IR and HDL-C.

关 键 词：代谢综合征X 前列腺增生 老年人 

分 类 号：R697.32[医药卫生—泌尿科学]