异体骨垫与聚醚醚酮融合器在颈椎融合术中的对比研究  

Comparison study on cage-shaped demineralized bone and poleyther ether ketone in cervical interbody fusion

作　　者：赵晨光[1] 关玉成[1] 汪伟基[1] 贾勇[1] 杜永红[1] 冯毅[1] 梁景灏[1] 

机构地区：[1]兰州军区乌鲁木齐总医院全军骨科中心,乌鲁木齐830000

出　　处：《中国矫形外科杂志》2013年第11期1081-1085,共5页Orthopedic Journal of China

摘　　要：[目的]通过与聚醚醚酮(polyether ether ketone PEEK)颈椎融合器比较,评价同种异体骨垫在颈椎前路椎间融合术中的疗效。[方法]对46例颈椎病患者行颈椎前路减压、椎间融合内固定术,根据材料不同,分为同种异体骨垫组(A组)和聚醚醚酮颈椎融合器组(B组),术后随访24个月。参照日本骨科协会(JOA)评分标准,评价指标为颈椎间隙融合率,融合时间,手术时间,术中出血及排斥反应。[结果]术后24个月异体骨垫组JOA评分13.1分,高于聚醚醚酮融合器组的12.8分,但无统计学差异(P>0.05)。A、B组术后有效融合率分别为96.0%和95.2%,无统计学差异(P>0.05)。A组与B组比较手术时间、术中出血及椎间隙高度无统计学差异(P>0.05)。两组内固定物均牢靠无松动,A组有1例出现轻微排斥反应。[结论]与聚醚醚酮(PEEK)颈椎融合器相比,同种异体骨垫不但有着优越的生物弹性模量,可靠的稳定性及不可比拟的天然骨诱导性,还可以个性化匹配符合椎间隙的生理形状,在临床应用中取得了满意的融合效果,值得临床广泛推广应用。[ Objective] To evaluate the effect of anterior cervical interbody fusion with self - designed cage - shaped demi- neralized bone （SCDB） by comparison poleyther ether ketone （PEEK） . [ Methods] From January 2005 to December 2009, 46 cases were enrolled in this study, depending on the graft material, cases were divided into SCDB group （group A） and PEEK group （B）, duration was 24 months. The postoperative effect was measured using Japanese Orthopaedic Association （JOA） score, cervical fusion rate, fusion time, operative time, blood loss and rejection rate. [ Results] The JOA score of two groups were 13.1 and 12. 8, with no significant difference （P 〉 0. 05） . Cervical fusion rate were 96. 0% and 95.2% in two groups, with no significant difference （ P 〉 0. 05 ） . Operative time, blood loss and intervertebral height change were equal in two groups. Two sets of cervical interbody fusion were solid fused, with one case of rejection in group during the follow - up. [ Con- clusion] Compared with PEEK, the results of anterior cervical interbody fusion with SCDB are satisfactory. It is worthy of clini- cal application.

关 键 词：异体骨垫 PEEK材料 颈椎间融合 

分 类 号：R687.3[医药卫生—骨科学]