对慢性腰腿痛患者注意偏向的事件相关电位研究  

Attentional biases toward event-related potential in patients with chronic lumbocrural pain

作　　者：陈国良[1] 路桂军[2] 单墨水[1] 刘智慧[2] 高谦[3] 崔红[1] 

机构地区：[1]解放军总医院/解放军医学院医学心理科,北京1008531 [2]解放军总医院/解放军医学院麻醉科,北京1008531 [3]解放军总医院/解放军医学院康复医学科,北京1008531

出　　处：《解放军医学院学报》2013年第6期596-599,共4页Academic Journal of Chinese PLA Medical School

基　　金：总装备部军队心理性课题(413EG65E)

摘　　要：目的探讨慢性腰腿痛患者对痛觉相关信息注意偏向机制研究。方法利用Neuroscan32导脑电工作站记录并比较慢性腰腿痛患者及健康对照组各16例对3类词汇(中性、痛觉、威胁)颜色命名的反应时,同时记录其32导联的事件相关电位(event-related potentials,ERP)脑电特征。结果慢性腰腿疼痛患者对痛觉相关词汇反应时长于中性词汇;威胁性词汇在两组被试各脑区诱发P200幅值显著高于中性词汇;慢性腰腿痛患者疼痛相关词汇诱发P300幅值显著高于中性词汇。结论慢性腰腿痛患者存在对痛觉相关信息的注意偏向,其产生机制可能与情绪控制加工有关;两组对威胁性信息均存在注意偏向可能与情绪的自动加工有关。Objective To study the mechanism underlying attentional biases toward event-related potential （ERP） in patients chronic lumbocrural pain. Methods Sixteen patients with chronic lumbocrural pain served as an experimental group and 16 healthy subjects served as a control group in this study. Their responses to the neutral, painful and threatening words and the ERP on 32-lead ECG were recorded with a NeuroScan workstation. Results The response time was longer to pain-related words than to neutral words and the P200 amplitude value of threatening words was significantly higher than that of neural words in patients with chronic lumbocrural pain. Conclusion Attentional biases toward pain- related information can be found in patients with chronic lumbocrural pain, which may be related with their emotional control !arocess.

关 键 词：慢性疼痛 注意偏向 事件相关电位 对照研究 

分 类 号：R441[医药卫生—诊断学]