穴位按压及经络拍打结合循证护理缓解奥沙利铂神经毒性的疗效观察  

Effect of Acupressure and Meridian Tapping Combined with Evidence-based Care on Relief of Oxaliplatin Neurotoxicity

作　　者：王英[1] 郑广[1] 

机构地区：[1]齐齐哈尔医学院附属第三医院肿瘤科,黑龙江省齐齐哈尔市161000

出　　处：《中国全科医学》2013年第13期1556-1558,共3页Chinese General Practice

基　　金：2012年黑龙江省齐齐哈尔市科技局科学技术研究计划课题

摘　　要：目的了解穴位按压及经络拍打结合循证护理在缓解奥沙利铂外周感觉神经毒性方面的应用效果。方法选择我院2009年1月—2012年5月85例消化系统肿瘤患者进行护理观察,分层随机化方法分为对照组(n=40)及观察组(n=45)。对照组仅采用一般护理方法;观察组采用循证护理方法,同时结合穴位按压、经络拍打护理。观察两组患者的外周感觉神经毒性分级情况、肢体疼痛、外周感觉神经毒性情况以及静脉炎发生情况。结果两组患者的外周感觉神经毒性、肢体疼痛方面差异有统计学意义(P<0.05)。肢体麻木(40.0%比17.8%)、蚁行感(35.0%比15.6%)、肢体活动障碍(17.5%比2.2%)、感觉丧失(10.0%比0)、静脉炎(25.0%比4.4%)方面差异均有统计学意义(P<0.05)。结论穴位按压及经络拍打结合循证护理能有效缓解奥沙利铂引起的外周感觉神经毒性,具有良好的应用效果。Objective To investigate the effect of acupressure and meridian tapping combined with evidence - based care on relief of oxaliplatin neurotoxicity. Methods Eighty - five patients undergoing nursing observation in our hospital between January 2009 and May 2012 were randomly divided into the control group （n = 40） and the observation group （n = 45 ）. Patients in the control group only received regular nursing care, while those in the observation group received evidence - based nursing care combined with acupressure and meridian tapping. Peripheral sensory neurotoxicity grading, limb pain, peripheral sensory neurotoxicity, and phlebitis were observed on patients in these two groups. Results Significant differences were observed between the two groups in peripheral sensory neurotoxieity and limb pain （ P 〈 0. 05 ）. The two groups also significantly differed in inci- dence of numbness （ 40.0% vs. 17.8% ） , formication （ 35.0% vs. 15.6% ）, limb movement disorder （ 17.5% vs. 2.2% ）, loss of sensation （ 10.0% vs. 0）, and phlebitis （25.0% vs. 4.4% ） （P 〈 0.05） . Conclusion Acupressure and meridian tapping combined with evidence - based nursing care can effectively alleviate the oxaliplatin - induced toxicity of periph- eral sensory nerve..

关 键 词：奥沙利铂 循证护理 穴位按压 经络拍打 神经毒性 

分 类 号：R595.479.1[医药卫生—内科学]