电针治疗带状疱疹随机对照试验系统评价  

Systematic review of randomized controlled trials of electro-acupuncture for herpes zoster

作　　者：陈立志[1] 谢伟想[2] 樊莉[1] 梁志唯[1] 张虹[2] 

机构地区：[1]广东省中医院传统疗法科,广东广州510006 [2]广州中医药大学第二临床医学院

出　　处：《河北中医》2013年第4期593-596,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：国家科技支撑计划课题(编号:2008BAI53B061)

摘　　要：目的评价电针治疗带状疱疹的临床疗效和安全性。方法计算机检索中、英文医学数据库,同时手工检索中医各类杂志和综合期刊,纳入有关电针治疗带状疱疹的随机对照试验文献,由2名评价者独立提取资料并进行方法学质量评估。统计学分析采用RevMan5.0软件。结果 9个研究(共560例患者)符合纳入标准,除1个研究为高质量文献外,其余8个研究均为低质量文献。系统评价结果显示,与西药组比较,电针组带状疱疹的痊愈率升高,视觉模拟评分(VAS评分)及临床症状评分降低,结痂及疼痛持续时间缩短,差异有统计学意义。结论从现有临床证据来看,电针治疗带状疱疹优于西医抗病毒治疗,但目前的研究病例总数较小,且纳入试验的方法学质量普遍较低,为得出更加可靠的结论,有必要进一步开展大样本、高质量的临床试验。Objective To evaluate the clinical efficacy and safety of electro-acupuncture on herpes zoster.Methods Randomized controlled trials(RCTs) involving electro-acupuncture in the treatment of herpes zoster were identified from CBM,CNKI,VIP,Wanfang Database and Pubmed.Relevant journals of traditional Chinese medicine and comprehensive journals were manually searched.The data were extracted and evaluated by two reviewers independently with a specially designed extraction form.The Cochrane Collaboration's RevMan5.0 software was used for data analyses.Results A total of 9 trials involving 560 patients were included.1 trial was high quality,the other 8 trials were low quality.Systematic review showed that the clinical cure rate,the VAS scores,the clinical symptoms scores,the time of crusting,the duration of pain were superior to the western drugs group,no significant difference was noted between them.Conclusion The profit treated by electro-acupuncture on herpes zoster is superior to that in the control group from the clinical evidence.But the incorporation of the limited number of documents and the quality was not very good.To get more reliable conclusions,further large-scale trials are required to define the role of electro-acupuncture in the treatment of herpes zoster.

关 键 词：电针 疱疹 带状 随机对照试验 中医药学文献 系统分析 

分 类 号：R752.12[医药卫生—皮肤病学与性病学] R245.33[医药卫生—临床医学]