皮质醇增多症临床回顾分析  

Retrospective analysis of patients with hypercortisolism

作　　者：李丹丹[1] 白悦心[2] 庞妩燕[1] 

机构地区：[1]河南大学淮河医院内分泌科,河南开封475000 [2]郑州大学第一附属医院内分泌科,河南郑州450052

出　　处：《中国当代医药》2013年第16期53-54,共2页China Modern Medicine

摘　　要：目的探讨皮质醇增多症的临床表现、诊断和治疗方法。方法回顾性分析郑州大学第一附属医院2006年9月～2011年12月收治的81例皮质醇增多症患者的临床资料。结果术后2周血压恢复正常50例,3个月后所有患者血压、血钾、血糖均恢复正常,6～9个月后库欣综合征症状完全消失,术后病理诊断肾上腺腺瘤40例,肾上腺皮质癌2例,肾上腺皮质大结节样增生1例,肾上腺皮质束状带增生22例,肾上腺皮髓质增生16例。结论临床表现、生化检查和影像学检查三者结合可提高皮质醇增多症的确诊率,绝大多数患者可以得到确诊,针对病因治疗效果较好。Objective To investigate the clinical manifestation, diagnosis and treatment of hypercortisolism. Methods Clinical data of 81 cases of hypercortisolism patients in our hospital from September 2006 to December 2011 were analyzed retrospectively. Results Two weeks after operation, the blood pressure returned to normal in 50 cases; after 3 months, blood pressure, serum potassium, glucose of all patients were restored to normal, in 6-9 months, cushing syndrome symptoms completely disappeared. 40 cases of adrenal adenoma and 2 cases of carcinoma, 1 case of macronodular bilateral adrenal hyperplasia, 23 cases of zona fascicular hyperplasia and 16 cases of coexisting adrenal cortical and medullary hyperplasia were confirmed by pathology. Conclusion Clinical features, laboratory examination and imaging findings improve the diagnostic accuracy of hypercortisolism, most of all the cases could be finally diagnosed, and the corresponding specific theraphy has a satisfactory effect.

关 键 词：皮质醇增多症 肾上腺 诊断 

分 类 号：R58[医药卫生—内分泌]