我院儿童上呼吸道感染的抗菌药物使用分析  

Analysis of the application of antimicrobial agents in our hospital for upper respiratory tract infection of children

作　　者：冯智敏[1] 陈如大[1] 崔玉琼[2] 

机构地区：[1]广东省佛山市南海区人民医院药学科,广东佛山528200 [2]广东省佛山科学技术学院药学系,广东佛山528000

出　　处：《中国现代医生》2013年第16期135-137,共3页China Modern Doctor

摘　　要：目的了解我院儿童上呼吸道感染的抗菌药物使用情况,为防范抗菌药物滥用提供数据支持。方法随机选取我院2011年1月～2012年12月间儿童上呼吸道感染出院病例400例,分为非干预组(2011年)和干预组(2012年)各200例,对其抗菌药物使用率、用药品种、联合用药率和抗菌药物费用等情况进行统计分析。结果干预后抗菌药物的使用率从99.5%下降到84%,明显低于非干预组(P<0.05);联合使用率从12%降至8%,抗菌药物费用从(419.64±63.68)元降至(347.41±43.20)元;用药品种均以一二代头孢为主。结论我院对儿童抗菌药物使用所采取的一系列干预措施有效可行,降低了抗菌药物使用率和药费,但使用率还是过高,需进一步加强宣教和监管。Objective To investigate the present status of antibiotics use in our hospital for upper respiratory tract infection of children. It was amied at providing data support for preventing antibiotic abuse. Methods The children with upper respiratory tract infection in our hospital from January 2011 to December 2012,were divided into control group （2011） of 200 cases and intervention group （2012） of 200 cases. The kind of drugs, the expense of antibacterial drugs, the rate of antibiotics use and drug combination were statistically analyzed. Results The rate of antibiotics use of inter- vention group was decreased from 99.5% to 84%, was lower than control group （P 〈 0.05 ）;the rate of drug combina- tion was decreased from 12% to 8%, the expense of antibiotics was decreased from （419.64＋63.68） to （347.41＋43.20）; The most frequently used drugs were the first and the second-generation cephalosporins. Conclusion A series of mea- sures taken in our hospital on the antibiotics use was feasible and effective, to improve the rationality and lower the cost of antibacterial drugs. However, antibacterials were still overused in our hospital. The rationality of antibacterial use needed to be further improved.

关 键 词：上呼吸道感染 抗菌药物 合理用药 使用分析 

分 类 号：R725.6[医药卫生—儿科]