妥洛特罗贴剂治疗毛细支气管炎疗效观察  

Effect of Tulobuterol Patches on Bronchiolitis

作　　者：赵浦[1] 梁洁竞[1] 王毅[1] 孙禄[1] 袁迅玲[1] 

机构地区：[1]黑龙江省医院儿科,黑龙江哈尔滨150036

出　　处：《中国伤残医学》2013年第5期18-20,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:观察妥洛特罗贴剂治疗婴幼儿毛细支气管炎的临床疗效。方法:将71例毛细支气管炎患儿随机分为治疗组(36例)和对照组(35例)。2组均给予相同的综合治疗,治疗组另给予妥洛特罗贴剂(阿米迪,0.5mg/贴),每晚20时贴于前胸或背部;对照组给予盐酸丙卡特罗片(美普清片)1μg/kg睡前1次口服。疗程7天。观察2组患儿主要症状、体征消失的时间,计算不良反应发生率。结果:治疗组喘憋消失时间及肺部喘鸣音消失时间、咳嗽消失时间均短于对照组,差异有统计学意义。治疗组有1例(2.8%)发生局部皮肤发红瘙痒,对照组8例(22.9%)发生不良反应,2组不良反应发生率组间差异有统计学意义(P<0.05)。结论:妥洛特罗贴剂治疗小儿毛细支气管炎显效快,副作用小,依从性好,疗效确切。Objective：To observe the therapeutic effect of tulobuterol patches infant bronchiolitis Methods： Seventy-one bronchiolitis infants were randomly divided into groups therapy （n=36）, control （n=35）. Both were given the same comprehensive treatment （anti-inflammatory, anti-virus, cough relieving phlegm dissipation, etc）, and the therapy group given additional tulobuterol patches（0.5mg） affixed to chest at bedtime, the control given procaterol hydrochloride tablet, 1μg/kg orally once at bedtime. The courses lasted 7d . Themajor symptoms, sign disappearance time and treatment time were observed, and the incidence of adverse reactions calculated to evaluate therapeutic effect. Results： The extinction time of asthma, lung wheezing, cough were all shorter in therapy group than in control group（P,0.05）. Localized skin redness occurred in 1 patient of therapy group（2.8%）, adverence reactions in 4 of control group （11.4%）, the difference was significant （P0.05）. Conclusion： Tulobuterol patches have a certain effect in treatment of infant bronchiolitis, with faster effect, fewer adverse reactions and good compliance.

关 键 词：毛细支气管炎 妥洛特罗贴剂 婴儿 

分 类 号：R562.2[医药卫生—呼吸系统]