缩宫素引产持续时间与宫缩乏力性产后出血的相关性  

Relativity between the duration of labor induction by oxytocin and postpartum hemorrhage caused by uterine atony

作　　者：赵丽琴[1] 郭遂群[1] 林丹[1] 尹文娇[2] 

机构地区：[1]南方医科大学第三附属医院妇产科,广东广州510630 [2]中国疾病预防控制中心病毒病预防控制所,北京102206

出　　处：《现代医学》2013年第5期332-335,共4页Modern Medical Journal

摘　　要：目的:分析小剂量缩宫素引产用药持续时间与宫缩乏力性产后出血相关性。方法:对符合引产指征的晚期妊娠孕妇予小剂量缩宫素引产,进行临床资料的回顾性分析,比较用药24、48、72 h内分娩宫缩乏力性产后出血发生率。结果:予小剂量缩宫素引产,在24 h内分娩的产妇与正常分娩产妇宫缩乏力性产后出血发生率差异无统计学意义(P>0.05)。用药48、72 h内分娩宫缩乏力性产后出血发生率明显增加,且随着时间的延长宫缩乏力性产后出血发生率呈现递增趋势(P<0.05)。结论:缩宫素引产用药持续时间越久,宫缩乏力性产后出血发生几率越大。对于开始静脉滴注缩宫素引产24 h仍未分娩的产妇,提早做好产后出血的抢救工作很有必要。Objective： To analyse the relativity between the duration of labor induction by oxytocin and postpartum hemorrhage caused by uterine atony. Methods： A retrospective analysis of the clinical data of the induction of labor by small-dose oxytocin injection on puerpera in late pregnancy who complies with the indicators of labor induction, and a compare of the occurrence rates of postpartum hemorrhage caused by uterine atony within 24, 48, and 72 hours of oxytocin injection were done. Results： There was no notable difference between the occurrence rates of postpartum hemorrhage in a puerpera who had received oxytocin injection within 24 hours to induce labor and one who underwent normal delivery process （ P 〉 0.05 ）. The occurrence rate of postpartum hemorrhage caused by uterine atony was significantly higher in a puerpera who delivered after 24-48 hours or 48-72 hours of oxytocin injection. Moreover, the occurrence rate of postpartum hemorrhage caused by uterine atony presented an increasing trend with the extension of the duration （ P 〈 0.05）. Conclusion： The longer the duration of labor induction by oxytocin, the greater the chance of occurrence of postpartum hemorrhage caused by uterine atony is. For a puerpera who is not in parturition after 24 hours of oxytocin injection, it is necessary to prepare for emergency treatment of postpartum hemorrhage in advance.

关 键 词：缩宫素 引产 宫缩乏力 产后出血 

分 类 号：R714.45[医药卫生—妇产科学] R714.461[医药卫生—临床医学]