氟砷联合作用对大鼠子代脑组织影响的电镜观察  

Observation on Offsprings' Brain Tissue of Parents Rats Exposed to Fluoride and Arsenic with Electron Microscope

作　　者：谢瑶芸[1] 胡汉华[1] 汤建安[1] 谢凤莲[1] 王新英 张晨[1] 姚华[1] 

机构地区：[1]新疆医科大学,新疆乌鲁木齐830054

出　　处：《地方病通报》2000年第2期7-8,共2页Endemic Diseases Bulletin

基　　金：国家自然科学基金资助项目!(39560075)

摘　　要：为探讨氟砷联合作用对大鼠子代大脑超微结构的影响 ,采用两代一窝繁殖试验的方法 ,对染毒大鼠子代大脑组织进行了电镜观察 ,结果显示各染毒组脑神经组织在超微结构上均有一定程度的改变 ,并随染毒剂量增加 ,病变程度加重 ,但脱毒组有所好转 。In order to explore the effects of fluoride and arsenic on the offsprings nervous system of the exposed rats, with a twogeneration reproductive test, the changes of rat offsprings brain, whose parents exposed to the different doses of fluoride and arsenic, were observed under the electron microscope. The offsprings nervous cells of every group have changed to some extent and the pathological changes became serious because of the dose increasing, while the changes of offsprings nervous cells lightened after stopping exposure to fluoride and arsenic. Fluoride and arsenic have some influences on offsprings of the exposed parents.

关 键 词：砷 氟 联合作用 超微结构 脑组织 电镜 神经毒性 

分 类 号：R995[医药卫生—毒理学] R361.3[医药卫生—药学]