速度矢量成像技术对急性期川崎病患儿左心收缩功能的评价  

Velocity Vector Imaging for the Evaluation of Left Ventricular Systolic Function of Children with Acute Kawasaki Disease

作　　者：刘金桥[1] 陈文娟[2] 张号绒[2] 何静波[2] 陈卓兰[2] 周启昌[1] 

机构地区：[1]中南大学湘雅二医院,湖南长沙410011 [2]湖南省儿童医院,湖南长沙410007

出　　处：《医学临床研究》2013年第5期833-834,837,共3页Journal of Clinical Research

基　　金：国家自然科学基金资助（项目批准号30970838）;中南大学湘雅二医院在职研究生,现在湖南省儿童医院工作;

摘　　要：【目的】使用速度矢量成像（VVI）技术评价急性期川崎病（KD）患儿的左心室纵向收缩功能，探讨VVI对于急性期KD患儿左心收缩功能的诊断价值。【方法】对32例临床确诊KD急性期患儿，根据有无冠状动脉扩张，将其分为冠脉扩张组、无冠脉扩张组两组，并与30例正常儿童左心室收缩功能数据对照，常规测量左心室射血分数（EF），左室缩短率（FS），每搏量（SV），使用VVI技术测量左心室各节段最大纵向运动速度（Vp），应变（s），应变率（SR）。【结果】所有研究对象EF、FS、SV测值无统计学意义（P〉0．05）；冠脉扩张组、无冠状动脉扩张组Vp，S，SR均较正常对照组降低（P〈0．05）；冠状动脉扩张组较无冠状动脉扩张组的Vp，S，SR测值在基底段、中间段下降（P〈0．05）。【结论】常规超声心动图检测急性KD患儿左心整体功能正常时，VVI技术显示左心室收缩功能出现减退，提示VVI技术可以定量评估早期左心室收缩功能。[Ohjective]To explore the value of velocity vector imaging（VVI） technique for the diagnosis of left ventricular systolic function of children with Kawasaki disease in acute stage. [Methods] According to cor- onary artery diameter, 32 pediatric patients diagnosed as Kawasaki disease were divided into no coronary artery dilatation group and coronary dilation group. The data of left ventricular systolic function in 32 pediatric pa- tients with Kawasaki disease were compared with the data of 30 normal children. Left ventricular ejection frac- tion（EF）, left ventricular fraction shortening（FS） and stroke volume（SV） were measured. VVI was used to measure maximum longitudinal motion velocity（Vp）, strain（S） and strain rate（SR） of different segments in left ventricle. [Results] There was no significant difference in EF, FS and SV of all subjects（ P ~〉0.05）. Compared with normal control group, Vp, S and SR in both dilation group and no coronary artery dilatation group decreased（ P %0.05）. Compared with no coronary artery dilation group, Vp, S and SR values of basal segment and middle segment in coronary artery dilation decreased（ P %0.05）. [Conclusion] Routine echocar- diogram shows normal entire left cardiac function in pediatric patients with Kawasaki disease, while VVI shows the degeneration of left ventricular systolic function. It indicates that VVI can quantitatively assess early left ventricular systolic function.

关 键 词：黏膜皮肤淋巴结综合征 心室功能 左 

分 类 号：R725[医药卫生—儿科]