泛发性脓疱型银屑病51例临床分析  

Clinical Analysis of 51 Cases of Generalized Pustular Psoriasis

作　　者：廖金英[1] 雷梅珍[1] 罗娅[1] 吴明若[1] 

机构地区：[1]中国人民解放军一六九医院皮肤科,湖南衡阳421002

出　　处：《医学临床研究》2013年第5期899-901,共3页Journal of Clinical Research

摘　　要：【目的】探讨泛发性脓疱型银屑病（GPP）的临床特征及治疗方法。【方法】对51例住院GPP患者的临床资料进行回顾性分析。【结果】本组51例GPP主要诱发因素为感染20例（39．22％）及不正规应用糖皮质激素12例（23．53％）。发热及白细胞增高是其主要系统性临床表现，二者与病情具有相关性。应用糖皮质激素联合第二代维甲酸药物（阿维A）治疗11例患者取得良好效果，有效率达100％。【结论】糖皮质激素不推荐作为常规一线治疗药物，系统应用糖皮质激素联合阿维A可作为GPP治疗的首选方案。[Objective] To explore the clinical features and treatment methods of generalized pustular psoriasis（GPP）. [Methods]Clinical data of 51 inpatients with GPP were analyzed retrospectively. [Results]Infection（20 cases, 39.22%） and the improper use of corticosteroids（12 cases, 23.53%） were the main causes of GPP. Fever and leucocytosis were the primary systematic manifestations and correlated with the degree of GPP. Corticosteroids combined with second-generation retinoids（acitretin） for the treatment of 11 patients a- chieved good results, and the effective rate was 100%. [Conclusion] Corticosteroids are not recommended as the first-line therapy. Systemic corticosteroids combined with retinoids（acitretin） can be chosen as the first choice for the treatment of GPP.

关 键 词：银屑病 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]