慢性肾炎患者水钠潴留与PET相关性研究  

Correlation between PET and Retention of Water and Sodium of Chronic Glomerulonephritis

作　　者：石蕾[1] 赵轶文[1] 张小平[1,2] 单若明 

机构地区：[1]首都医科大学附属北京天坛医院肾内科 [2]首都医科大学临床检测中心

出　　处：《首都医科大学学报》2000年第2期118-119,共2页Journal of Capital Medical University

摘　　要：为研究慢性肾炎患者水钠潴留与血浆内皮素 (PET)的相关性 ,检测了伴或不伴水钠潴留慢性肾炎患者PET和 2 4h尿蛋白排泄量。发现伴水钠潴留组PET显著高于对照组 (P <0 .0 1 ) ,无水钠潴留组与对照组无显著差异(P >0 .0 5)。还发现水钠潴留组尿蛋白排泄量亦显著高于无水钠潴留组 (P <0 .0 1 ) ,但PET和尿蛋白排泄量无直接相关性 (r=0 .35,t=1 .2 3) ,推测PET可能在慢性肾炎的病理过程中起着重要作用 ,但与尿蛋白排泄量无直接关系。In order to study the correlation between retention of water and sodium of chronic glomerulonephritis and plasma endotheliolysin(PET). PET and 24 hours uric protein excretory volume were examined in chronic glomerulonephritis patients with or without retention of water and sodium, found that PET in the group with retention of water and sodium is obviously higher than that in the control group( P <0.01), and in the group without retenion of water and sodium,it is not obviously different from that in control group( P >0.05). It was also found that not only PET in the group with retention of water and sodium, but also the uric protein excretory volume is obviously higher than that in the group without retention of water and sodium. There is no linear correlation between PET and uric protein exeretory volume( r =0.35, t =1.23). So PET may play important role during the physiopathalogic process of chronic glomerulonephritis, but had no direct relation to uric protein excretory volume.

关 键 词：慢性肾炎 血浆内皮素 尿蛋白排泄量 

分 类 号：R692.3[医药卫生—泌尿科学]